The characteristics, occurrence, and toxicological effects of patulin

I Saleh, I Goktepe - Food and chemical toxicology, 2019 - Elsevier
Mycotoxins are the secondary metabolites secreted by different types of fungi to which
humans can get exposed mainly via ingestion. Patulin (C 7 H 6 O 4) is a polyketide lactone …

Biology of the cell cycle inhibitor p21CDKN1A: molecular mechanisms and relevance in chemical toxicology

I Dutto, M Tillhon, O Cazzalini, LA Stivala… - Archives of toxicology, 2015 - Springer
The cell cycle inhibitor p21 CDKN1A is a protein playing multiple roles not only in the DNA
damage response, but also in many cellular processes during unperturbed cell growth. The …

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

B Canal, AW McClure, JF Curran, M Wu… - Biochemical …, 2021 - portlandpress.com
SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world
causing a deadly pandemic with tremendous social and economic costs. Healthcare …

Toxicological effects of patulin mycotoxin on the mammalian system: an overview

S Pal, N Singh, KM Ansari - Toxicology research, 2017 - academic.oup.com
Abstract The mycotoxin PAT (4-hydroxy-4 H-furo [3, 2 c] pyran-2 [6 H]-one) is a secondary
metabolic product of molds such as Penicillium, Aspergillus, and Byssochlamys species …

Human skin penetration of selected model mycotoxins

J Boonen, SV Malysheva, L Taevernier… - Toxicology, 2012 - Elsevier
Dermal exposure data for mycotoxins are very scarce and fragmentary, despite their
widespread skin contact and hazard toxicity. In this study, the transdermal kinetics of …

Progress in the distribution, toxicity, control, and detoxification of patulin: A review

C Wei, L Yu, N Qiao, J Zhao, H Zhang, Q Zhai, F Tian… - Toxicon, 2020 - Elsevier
Patulin (PAT) is a secondary metabolite secreted by fungi in the genera Penicillium,
Aspergillus, and Enterobacter and is the most common mycotoxin found in apples and apple …

[HTML][HTML] The effects of mycotoxin patulin on cells and cellular components

S Ramalingam, A Bahuguna, M Kim - Trends in Food Science & …, 2019 - Elsevier
Background Several fungal taxa, including Aspergillus, Byssochlamys, and Penicillium
species produce the mycotoxin patulin in contaminated food materials. Patulin is an …

Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway

M Boussabbeh, I Ben Salem, A Prola… - Toxicological …, 2015 - academic.oup.com
Patulin (PAT) is a toxic metabolite produced by several filamentous fungi of the genera of
Penicillium, Aspergillus, and Byssochlamys. PAT is the most common mycotoxin found in …

Degradation of patulin in apple juice by pulsed light and its effect on the quality

Y Li, R Cai, C Fu, L Qi, Y Yuan, T Yue, Q Ge… - Food and Bioprocess …, 2023 - Springer
The objective of this study was to investigate the effect of pulsed light (PL) treatment on the
degradation of patulin in apple juice and its quality. The impact of different processing …

Olea europaea leaf (Ph. Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase

J Flemmig, K Kuchta, J Arnhold, HW Rauwald - Phytomedicine, 2011 - Elsevier
In Mediterranean folk medicine Olea europaea L. leaf (Ph. Eur.) preparations are used as a
common remedy for gout. In this in vitro study kinetic measurements were performed on both …