Introduction Patients with systemic sclerosis (SSc) have an increased risk of endothelial
dysfunction, atherosclerosis, and cardiovascular events compared to the general population …

ABSTRACT Objectives. Interleukin-6 (IL-6) may play a role in the pathogenesis of SSc. C-
reactive protein (CRP), an acute phase reactant induced by IL-6, may be a prognostic …

Natriuretic peptides (NPs) control natriuresis and normalize changes in blood pressure.
Recent studies suggest that NPs are also involved in the regulation of pain sensitivity …

Platelets are essential in maintaining blood homeostasis and regulating several
inflammatory processes. They constantly interact with immune cells, have immunoregulatory …

Objectives: Microparticles (MPs) may be involved in the pathogenesis of systemic sclerosis
(SSc), which includes vasculopathy, endothelial cell activation, and coagulation activation …

Raynaud's phenomenon (RP) describes the excessive vascular response of the digital
vessels in response to cold exposure and emotional stress. It is typically the earliest …

Background C-type natriuretic peptide (CNP) has anti-inflammatory, anti-proliferative, and
anti-migratory properties. During the past years, CNP has attained an increasing interest by …

The aim of the study was the assessment of the von Willebrand antigen (vWF Ag), E‐
selectin, and P‐selectin concentration in blood plasma of patients with pseudoexfoliation …

Raynaud's phenomenon (RP) describes excessive vasoconstriction of the digital
microvasculature in response to cold exposure and emotional stress. RP is typically the …

Twardzina ograniczona (localized scleroderma, morphea) znana również jako morphea jest
przewlekłą, autoimmunizacyjną jednostką chorobową o niewyjaśnionej dotychczas etiologii …