[HTML][HTML] Cancer stem cells in immunoregulation and bypassing anti-checkpoint therapy
E Rouzbahani, J Majidpoor, S Najafi… - Biomedicine & …, 2022 - Elsevier
Tumor microenvironment (TME) takes critical roles in tumor resistance to immune checkpoint
inhibitors (ICIs) including anti-programmed death-1 (PD-1) or anti-programmed death-ligand …
inhibitors (ICIs) including anti-programmed death-1 (PD-1) or anti-programmed death-ligand …
Mechanism and therapeutic potential of tumor-immune symbiosis in glioblastoma
Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor in human adults.
Myeloid-lineage cells, including macrophages, microglia, myeloid-derived suppressor cells …
Myeloid-lineage cells, including macrophages, microglia, myeloid-derived suppressor cells …
Artificial intelligence for prediction of response to cancer immunotherapy
Y Yang, Y Zhao, X Liu, J Huang - Seminars in Cancer Biology, 2022 - Elsevier
Artificial intelligence (AI) indicates the application of machines to imitate intelligent behaviors
for solving complex tasks with minimal human intervention, including machine learning and …
for solving complex tasks with minimal human intervention, including machine learning and …
VISTA immune regulatory effects in bypassing cancer immunotherapy: Updated
K Mortezaee, J Majidpoor, S Najafi - Life sciences, 2022 - Elsevier
Resistance to immune checkpoint inhibitors (ICIs) is a common predicament in cancer
immunotherapy, which requires urgent interventions. V-domain immunoglobulin suppressor …
immunotherapy, which requires urgent interventions. V-domain immunoglobulin suppressor …
The current landscape of spatial biomarkers for prediction of response to immune checkpoint inhibition
Enabling the examination of cell-cell relationships in tissue, spatially resolved omics
technologies have revolutionised our perspectives on cancer biology. Clinically, the …
technologies have revolutionised our perspectives on cancer biology. Clinically, the …
Nivolumab reaches brain lesions in patients with recurrent glioblastoma and induces T-cell activity and upregulation of checkpoint pathways
Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis. Although
immunotherapy is being explored as a potential treatment option for patients with GBM, it is …
immunotherapy is being explored as a potential treatment option for patients with GBM, it is …
The eclectic nature of glioma-infiltrating macrophages and microglia
Glioblastomas (GBMs) are complex ecosystems composed of highly multifaceted tumor and
myeloid cells capable of responding to different environmental pressures, including …
myeloid cells capable of responding to different environmental pressures, including …
[HTML][HTML] Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression
BACKGROUND Immune cell profiling of primary and metastatic CNS tumors has been
focused on the tumor, not the tumor microenvironment (TME), or has been analyzed via …
focused on the tumor, not the tumor microenvironment (TME), or has been analyzed via …
Organ-specific immunity: A tissue analysis framework for investigating local immune responses to SARS-CoV-2
Local immune activation at mucosal surfaces, mediated by mucosal lymphoid tissues, is vital
for effective immune responses against pathogens. While pathogens like severe acute …
for effective immune responses against pathogens. While pathogens like severe acute …
[HTML][HTML] Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
JAI Johnson, GL Stein-O'Brien, M Booth, R Heiland… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Cells are fundamental units of life, constantly interacting and evolving as dynamical systems.
While recent spatial multi-omics can quantitate individual cells' characteristics and …
While recent spatial multi-omics can quantitate individual cells' characteristics and …