The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …

Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

Mitochondrial DNA (mtDNA) is a potent agonist of the innate immune system; however, the
exact immunostimulatory features of mtDNA and the kinetics of detection by cytosolic nucleic …

Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

The rising dangers of bacterial infections have created an urgent need for the development
of a new generation of antibacterial technologies and therapeutics. Antibacterial …

Antibacterial photodynamic therapy had attracted considerable attention in implant-
associated infections treatment due to its high selectivity and no resistance. Actually …

Cyclic guanosine monophosphate (GMP)-AMP (cGAMP) synthase (cGAS) is a universal
double-stranded DNA (dsDNA) sensor that recognizes foreign and self-DNA in the …

Bacterial infection has been a severe concern of global health which seriously threatens
human lives. Particularly, drug-resistant bacteria and protective biofilm pose nonnegligible …

Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

Many bacteria in nature exist in multicellular communities termed biofilms, where cells are
embedded in an extracellular matrix that provides rigidity to the biofilm and protects cells …