Strategies for development of decellularized heart valve scaffolds for tissue engineering

Y Snyder, S Jana - Biomaterials, 2022 - Elsevier
Valvular heart diseases (VHDs) are currently treated using either mechanical or
bioprosthetic heart valves. Unfortunately, mechanical valves require lifelong anticoagulation …

Decellularized xenografts in regenerative medicine: From processing to clinical application

H Capella‐Monsonís, DI Zeugolis - Xenotransplantation, 2021 - Wiley Online Library
Decellularized xenografts are an inherent component of regenerative medicine. Their
preserved structure, mechanical integrity and biofunctional composition have well …

Calcification in pulmonary heart valve tissue engineering: a systematic review and meta-analysis of large-animal studies

DC van der Valk, A Fomina, M Uiterwijk… - Basic to Translational …, 2023 - jacc.org
Tissue-engineered heart valves (TEHVs) are emerging alternatives to current valve
prostheses and prospectively a lifelong replacement. Calcification, a pathological …

[HTML][HTML] Failure of decellularized porcine small intestinal submucosa as a heart valved conduit

JW van Rijswijk, H Talacua, K Mulder… - The Journal of thoracic …, 2020 - Elsevier
Objective Decellularized extracellular matrix made from porcine small intestinal submucosa,
commercially available as CorMatrix (CorMatrix Cardiovascular, Inc, Roswell, Ga) is used off …

[HTML][HTML] Functional regeneration at the blood-biomaterial interface

DM Ibrahim, A Fomina, CVC Bouten… - Advanced Drug Delivery …, 2023 - Elsevier
The use of cardiovascular implants is commonplace in clinical practice. However,
reproducing the key bioactive and adaptive properties of native cardiovascular tissues with …

Mechano-regulated cell–cell signaling in the context of cardiovascular tissue engineering

C Karakaya, JGM van Asten, T Ristori… - … and modeling in …, 2022 - Springer
Cardiovascular tissue engineering (CVTE) aims to create living tissues, with the ability to
grow and remodel, as replacements for diseased blood vessels and heart valves. Despite …

Pulmonary valve tissue engineering strategies in large animal models

M Uiterwijk, DC van der Valk, R van Vliet… - Plos one, 2021 - journals.plos.org
In the last 25 years, numerous tissue engineered heart valve (TEHV) strategies have been
studied in large animal models. To evaluate, qualify and summarize all available …

From Scan to Simulation—A Novel Workflow for Developing Bioinspired Heart Valves

A Lee, S Farajikhah, M Crago… - Journal of …, 2023 - asmedigitalcollection.asme.org
Current heart valve replacements lack durability and prolonged performance, especially in
pediatric patients. In part, these problems may be attributed to the materials chosen for these …

Extracorporeal life support as bridge to recovery in yew poisoning: case reports and literature review

J Hermes‐Laufer, M Meyer, A Rudiger… - ESC heart …, 2021 - Wiley Online Library
Aims This short communication aims to review the treatment of cardiogenic shock in patients
with yew poisoning based on two case reports from our institution, focusing on the use of …

Use of four‐layer porcine small intestinal submucosa alone as a scaffold for the treatment of deep corneal defects in dogs and cats: preliminary results

L Barachetti, M Zanni, D Stefanello… - Veterinary …, 2020 - Wiley Online Library
Background To describe the efficacy of four‐layer porcine small intestinal submucosa (Vetrix
BioSIS plus+) as single scaffold for the treatment of deep corneal lesions in dogs and cats …