Renal disease and systemic sclerosis: an update on scleroderma renal crisis

A Cole, VH Ong, CP Denton - Clinical reviews in allergy & immunology, 2023 - Springer
Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc)
with a mortality of 20% at 6 months. Once the leading cause of mortality in scleroderma …

[PDF][PDF] One year in review 2020: systemic sclerosis

M Orlandi, G Lepri, A Damiani, S Barsotti… - Clin Exp …, 2020 - clinexprheumatol.org
Systemic sclerosis (SSc) is a connective tissue disease characterised by diffuse
microangiopathy and immune dysregulation which ultimately results in widespread fibrosis …

Assessment of kidney involvement in systemic sclerosis: From scleroderma renal crisis to subclinical renal vasculopathy

A Gigante, G Leodori, C Pellicano, A Villa… - The American Journal of …, 2022 - Elsevier
The spectrum of kidney involvement in systemic sclerosis (SSc) includes scleroderma renal
crisis, widely recognized as the most severe renal-vascular complication, but also several …

Quantitative analysis of pulmonary vasculature in systemic sclerosis at spirometry-gated chest CT

M Occhipinti, C Bruni, G Camiciottoli… - Annals of the …, 2020 - ard.bmj.com
Objective To prospectively investigate whether differences in pulmonary vasculature exist in
systemic sclerosis (SSc) and how they are distributed in patients with different pulmonary …

The renal resistive index: a new biomarker for the follow-up of vascular modifications in systemic sclerosis

A Gigante, C Bruni, G Lepri, G Tesei… - The Journal of …, 2021 - jrheum.org
Objective. The aim of the present retrospective observational study was to evaluate the
change of Renal Resistive Index (RRI) over time (ΔRRI) and under treatment in patients with …

Estimated glomerular filtration rate and renal resistive index as possible predictive markers of mortality in systemic sclerosis

G Leodori, C Pellicano, A Gigante, E Rosato - European Journal of Internal …, 2021 - Elsevier
Objective Subclinical nephropathy is underestimated in systemic sclerosis (SSc). Study aim
is to evaluate the role of renal resistance indices (RRI) and estimated glomerular filtration …

Evaluation of intra-renal stiffness in patients with primary aldosteronism

L Petramala, A Concistrè, F Circosta, A Gigante… - High Blood Pressure & …, 2022 - Springer
Intorduction Aldosterone is known to play important role in developing cardiovascular,
metabolic, renal damage in hypertensive patients. Aim Aim of study was to evaluate …

Prediction and primary prevention of major vascular complications in systemic sclerosis

C Bruni, L Cometi, A Gigante, E Rosato… - European Journal of …, 2021 - Elsevier
Abstract Objective In Systemic Sclerosis (SSc), vasculopathy is the background of major
vascular complications (MVCs), like digital ulcers (DUs), pulmonary arterial hypertension …

Bosentan does not affect renal resistive index in scleroderma/systemic sclerosis patients

E Di Poi, GL Colussi, M Bertoni, I Giovannini… - Kidney and Blood …, 2023 - karger.com
Introduction: If properly evaluated, chronic kidney disease can be found in up to 50% of
patients with systemic sclerosis (SSc). The renal resistive index (RRI) is a marker of …

Neurological, cardiac, musculoskeletal, and renal manifestations of scleroderma along with insights into its genetics, pathophysiology, diagnostic, and therapeutic …

P Prajjwal, MDM Marsool, V Yadav… - Health Science …, 2024 - Wiley Online Library
Background Scleroderma, also referred to as systemic sclerosis, is a multifaceted
autoimmune condition characterized by abnormal fibrosis and impaired vascular function …