Antimicrobial and structural properties of metal ions complexes with thiosemicarbazide motif and related heterocyclic compounds
E Namiecińska, M Sobiesiak, M Małecka… - Current Medicinal …, 2019 - ingentaconnect.com
Antibiotic resistance acquired by various bacterial fungal and viral pathogens poses
therapeutic problems of increasing severity. Among the infections that are very difficult to …
therapeutic problems of increasing severity. Among the infections that are very difficult to …
Design, synthesis, antibacterial evaluations and in silico studies of novel thiosemicarbazides and 1, 3, 4-thiadiazoles
S Janowska, D Khylyuk, S Andrzejczuk, M Wujec - Molecules, 2022 - mdpi.com
The emergence of drug-resistant bacterial strains continues to be one of the major
challenges of medicine. For this reason, the importance of searching for novel structures of …
challenges of medicine. For this reason, the importance of searching for novel structures of …
Synthesis, in silico experiments and biological evaluation of 1, 3, 4-trisubstituted pyrazole derivatives as antimalarial agents
Abstract New 1, 3, 4-trisubstituted pyrazole derivatives were synthesized and evaluated for
their antiplasmodial activity. Compounds 4b, 4c, 7a and 7d were the most potent …
their antiplasmodial activity. Compounds 4b, 4c, 7a and 7d were the most potent …
Identifying and explaining the regioselectivity of alkylation of 1, 2, 4-triazole-3-thiones using NMR, GIAO and DFT methods
The regioselectivity of the alkylation of four 1, 2, 4-triazole-3-thiones with eight different
organic halides was determined by the comparison of experimentally observed NMR …
organic halides was determined by the comparison of experimentally observed NMR …
Investigations of Thiosemicarbazides as Botulinum Toxin Active-Site Inhibitors: Enzyme, Cellular, and Rodent Intoxication Studies
Botulinum neurotoxin type A (BoNT/A) is an exceptionally potent neurotoxin of great
therapeutic value; however, it is also considered a weapon of mass destruction, as it is one …
therapeutic value; however, it is also considered a weapon of mass destruction, as it is one …
Synthesis of cobalt hydroxide nano-flakes functionalized with glutamic acid and conjugated with thiosemicarbazide for anticancer activities against human breast …
In recent years, researchers were attracted to nanomaterials components for their potential
role in cancer treatment. This study aimed to develop a novel and biocompatible cobalt …
role in cancer treatment. This study aimed to develop a novel and biocompatible cobalt …
Naringenin Schiff base: antioxidant activity, acid–base profile, and interactions with DNA
A Schiff base derived from naringenin (NTSC) and its complex with Cu (II)([Cu (H 3 L)(OAc)]·
H 2 O, Cu (II)–NTSC) have been synthesized and characterized by physicochemical and …
H 2 O, Cu (II)–NTSC) have been synthesized and characterized by physicochemical and …
Antitumor activity and physicochemical properties of new thiosemicarbazide derivative and its Co (II), Ni (II), Cu (II), Zn (II) and Cd (II) complexes
B Rogalewicz, A Climova, E Pivovarova, J Sukiennik… - Molecules, 2022 - mdpi.com
A novel biologically active thiosemicarbazide derivative ligand L (N-[(phenylcarbamothioyl)
amino] pyridine-3-carboxamide) and a series of its five metal (II) complexes, namely:[Co (L) …
amino] pyridine-3-carboxamide) and a series of its five metal (II) complexes, namely:[Co (L) …
Synthesis and Diverse Pharmacological Actions of Thiosemicarbazide Analogs: A Review
V Jindaniya, R Mishra, A Mazumder… - Letters in Drug Design …, 2024 - benthamdirect.com
Background: Thiosemicarbazide is an important substance in the synthesis of
pharmacological and bioactive substances, and it is commonly used in the discovery of new …
pharmacological and bioactive substances, and it is commonly used in the discovery of new …
Design, Synthesis, DNA Binding, and Docking Studies of Thiazoles and Thiazole‐Containing Triazoles as Antibacterials
R Santosh, MK Selvam, SU Kanekar… - …, 2018 - Wiley Online Library
A series of thiazoles 4 a‐g and thiazole clubbed triazoles 5 a‐f were synthesized and
showed good antibacterial activity against, Pseudomonas aeruginosa, Escherchia coli …
showed good antibacterial activity against, Pseudomonas aeruginosa, Escherchia coli …