[HTML][HTML] Regulatory elements in the viral genome

HU Bernard - Virology, 2013 - Elsevier
The small DNA genomes of papillomaviruses contain a surprisingly large number of
regulatory or cis-responsive elements, which regulate replication and transcription of the …

Relationship between steroid hormone contraceptives and HPV, cervical intraepithelial neoplasia and cervical carcinoma

EM de Villiers - International journal of cancer, 2003 - Wiley Online Library
Available data demonstrate an increase in the transcription of high‐risk papillomaviruses by
the 16α‐hydroxylation of estrogens, which is in line with the epidemiologic data showing an …

Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes

M Hummel, JB Hudson, LA Laimins - Journal of virology, 1992 - Am Soc Microbiol
The expression of viral genes during the productive life cycle of human papillomaviruses
(HPV) is tightly coupled to the differentiation program of epithelial cells. We have examined …

Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells

S Mahata, AC Bharti, S Shukla, A Tyagi, SA Husain… - Molecular cancer, 2011 - Springer
Background-Specific types of high risk Human papillomaviruses (HR-HPVs) particularly,
HPV types 16 and 18 cause cervical cancer and while the two recently developed vaccines …

Evolution of human papillomavirus type 18: an ancient phylogenetic root in Africa and intratype diversity reflect coevolution with human ethnic groups

CK Ong, SY Chan, MS Campo, K Fujinaga… - Journal of …, 1993 - Am Soc Microbiol
Papillomaviruses are an ideal model system for the study of DNA virus evolution. On several
levels, phylogenetic trees of papillomaviruses reflect the relationship of their hosts …

Identification of a differentiation-inducible promoter in the E7 open reading frame of human papillomavirus type 16 (HPV-16) in raft cultures of a new cell line …

K Grassmann, B Rapp, H Maschek, KU Petry… - Journal of …, 1996 - Am Soc Microbiol
Gene expression of human papillomaviruses (HPV) is tightly linked to differentiation
processes within the pluristratified epithelium. To analyze changes in the transcription …

Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind

SY Chan, L Ho, CK Ong, V Chow, B Drescher… - Journal of …, 1992 - Am Soc Microbiol
We have amplified by the polymerase chain reaction, cloned, and sequenced genomic
segments of 118 human papillomavirus type 16 (HPV-16) isolates from 76 cervical biopsy …

The enhancer of human papillomavirus type 16: binding sites for the ubiquitous transcription factors oct-1, NFA, TEF-2, NF1, and AP-1 participate in epithelial cell …

T Chong, D Apt, B Gloss, M Isa, HU Bernard - Journal of Virology, 1991 - Am Soc Microbiol
The enhancer of human papillomavirus type 16 (HPV-16) is considered to be specific for
epithelial cells, in particular for cervical carcinoma-derived cell lines. We reexamined this …

Differential expression and activation of NF‐κB family proteins during oral carcinogenesis: Role of high risk human papillomavirus infection

A Mishra, AC Bharti, P Varghese… - … journal of cancer, 2006 - Wiley Online Library
Oral cancer is one of the most common cancers in India and south‐east Asian region
consisting of more than 50% of all malignant tumors. Along with many known risk factors …

Sequence variants of human papillomavirus type 16 in clinical samples permit verification and extension of epidemiological studies and construction of a phylogenetic …

L Ho, SY Chan, V Chow, T Chong, SK Tay… - Journal of clinical …, 1991 - Am Soc Microbiol
Genomic variability between different viral isolates provides a powerful epidemiological tool
for verifying ultrasensitive diagnostic procedures, understanding infectious pathways in …