Easily established and multifunctional synthetic nanobody libraries as research tools

B Liu, D Yang - International Journal of Molecular Sciences, 2022 - mdpi.com
Nanobodies, or VHHs, refer to the antigen-binding domain of heavy-chain antibodies
(HCAbs) from camelids. They have been widely used as research tools for protein …

Shark new antigen receptor (IgNAR): structure, characteristics and potential biomedical applications

SN Juma, X Gong, S Hu, Z Lv, J Shao, L Liu, G Chen - Cells, 2021 - mdpi.com
Shark is a cartilaginous fish that produces new antigen receptor (IgNAR) antibodies. This
antibody is identified with a similar human heavy chain but dissimilar sequences. The …

Zika virus serological diagnosis: commercial tests and monoclonal antibodies as tools

IBB Silva, AS Silva, MS Cunha, AD Cabral… - Journal of Venomous …, 2020 - SciELO Brasil
Zika virus (ZIKV), an emerging arthropod-borne virus (arbovirus) of the Flaviviridae family, is
a current issue worldwide, particularly because of the congenital and neurological …

Development of a recombinant monospecific anti-PLGF bivalent nanobody and evaluation of it in angiogenesis modulation

A Nikooharf, R Arezumand, K Mansouri… - Molecular …, 2020 - Springer
During the past two decades, tumor therapy based on monoclonal antibody has been found
as a confident therapeutic approach in solid tumors and hematologic malignancies …

[PDF][PDF] Antibody Therapy: Past, Present and Future

D Moitra, PA Miraclin, N Gul, P Sen - Austin Biochem, 2021 - researchgate.net
The emergence of pandemics like SARS-CoV-2 and a gradual increase in Multidrug
Resistant (MDR) infections highlights the need of innovation in therapeutics. Antibodies are …

The emerging role of mass spectrometry in structural biology

EB Erba - 2018 - cnrs.hal.science
Biological mass spectrometry (MS) is an important analytical approach to assess the mass of
biomolecules with high accuracy, sensitivity and speed of analysis. It has wide applications …