W van Leeuwen, C Rabouille - Traffic, 2019 - Wiley Online Library
In cells at steady state, two forms of cell compartmentalization coexist: membrane‐bound organelles and phase‐separated membraneless organelles that are present in both the …
Processing bodies (PBs) and stress granules (SGs) are prominent examples of subcellular, membraneless compartments that are observed under physiological and stress conditions …
The final step of cytoplasmic mRNA degradation proceeds in either a 5′‐3′ direction catalysed by Xrn1 or in a 3′‐5′ direction catalysed by the exosome. Dis3/Rrp44, an …
Cells have developed protein quality-control strategies to manage the accumulation of misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission …
S Lev, D Desmarini, M Chayakulkeeree, TC Sorrell… - PloS one, 2012 - journals.plos.org
Cryptococcus neoformans survives host temperature and regulates cell wall integrity via a calcium-dependent phosphatase, calcineurin. However, downstream effectors of C …
T Grousl, J Vojtova, J Hasek, T Vomastek - Yeast, 2022 - Wiley Online Library
The formation of stress granules (SGs), membrane‐less organelles that are composed of mainly messenger ribonucleoprotein assemblies, is the result of a conserved evolutionary …
M Lindström, L Chen, S Jiang, D Zhang, Y Gao… - Nature …, 2022 - nature.com
Stress granules (SGs) are non-membranous organelles facilitating stress responses and linking the pathology of age-related diseases. In a genome-wide imaging-based phenomic …
S Kramer, B Bannerman-Chukualim, L Ellis… - PLoS …, 2013 - journals.plos.org
The number of paralogs of proteins involved in translation initiation is larger in trypanosomes than in yeasts or many metazoan and includes two poly (A) binding proteins …
Due to their short lifespan, rapid division, and ease of genetic manipulation, yeasts are popular model organisms for studying aging in actively dividing cells. To study replicative …