[HTML][HTML] Artificial intelligence in the diagnosis and management of colorectal cancer liver metastases

G Rompianesi, F Pegoraro, CDL Ceresa… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common malignancy worldwide, with
approximately 50% of patients developing colorectal cancer liver metastasis (CRLM) during …

Current surgical management of peri-hilar and intra-hepatic cholangiocarcinoma

A Lauterio, R De Carlis, L Centonze, V Buscemi… - Cancers, 2021 - mdpi.com
Simple Summary The treatment of peri-hilar (h-CCA) and intrahepatic (i-CCA)
cholangiocarcinoma is an evolving field in hepato-pancreato-biliary surgery. Continuous …

Cholangiocarcinoma: what are the options in all comers and how has the advent of molecular profiling opened the way to personalised medicine?

GS Roth, C Neuzillet, M Sarabi, J Edeline… - European Journal of …, 2023 - Elsevier
Cholangiocarcinoma is a deadly cancer comprising very heterogenous subtypes with a
limited therapeutic arsenal in all comers. However, recent significant advances were made …

Current perspectives on the surgical management of perihilar cholangiocarcinoma

DB Hewitt, ZJ Brown, TM Pawlik - Cancers, 2022 - mdpi.com
Simple Summary Perihilar cholangiocarcinoma is a rare disease with generally poor
outcomes. Complete surgical resection remains the only chance at long-term survival …

New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving …

L Colyn, G Alvarez-Sola, MU Latasa, I Uriarte… - Journal of Experimental …, 2022 - Springer
Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular
aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of …

Feasibility of machine learning-based modeling and prediction using multiple centers data to assess intrahepatic cholangiocarcinoma outcomes

SN Zhou, DW Jv, XF Meng, JJ Zhang, C Liu… - Annals of …, 2023 - Taylor & Francis
Background and aims Currently, there are still no definitive consensus in the treatment of
intrahepatic cholangiocarcinoma (iCCA). This study aimed to build a clinical decision …

Preneoplastic lesions in the liver: Molecular insights and relevance for clinical practice

E Desjonqueres, C Campani, F Marra… - Liver …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are the most frequent
primary liver cancers, accounting for approximately 80% and 15%, respectively. HCC …

Circulating cell-free DNA-based comprehensive molecular analysis of biliary tract cancers using next-generation sequencing

SL Csoma, J Bedekovics, G Veres, A Árokszállási… - Cancers, 2022 - mdpi.com
Simple Summary In the era of personalized oncology, next-generation sequencing plays an
important role in identifying mutations that may predict the molecular pathomechanism and …

[HTML][HTML] Pathological, molecular, and clinical characteristics of cholangiocarcinoma: A comprehensive review

M Vij, Y Puri, A Rammohan, G Gowripriya… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Cholangiocarcinomas are a heterogeneous group of highly aggressive cancers that may
arise anywhere within the biliary tree. There is a wide geographical variation with regards to …

[HTML][HTML] Intrahepatic cholangiocarcinoma biomarkers: Towards early detection and personalized pharmacological treatments

M Capuozzo, M Santorsola, F Ferrara, C Cinque… - Molecular and Cellular …, 2024 - Elsevier
Cholangiocarcinoma (CCA) is a rare malignancy originating from the biliary tree and is
anatomically categorized as intrahepatic (iCCA), perihilar, and extrahepatic or distal. iCCA …