Indole–a promising pharmacophore in recent antiviral drug discovery

A Dorababu - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
The bicyclic molecule indole has been in the limelight because of its numerous
pharmacological potencies. It is used as an excellent scaffold in drug discovery of medicinal …

Medicinal plants in the treatment of peptic ulcer disease: A review

H Ardalani, A Hadipanah… - Mini reviews in medicinal …, 2020 - ingentaconnect.com
Peptic Ulcer Disease (PUD) is the most common disorder of the stomach and duodenum,
which is associated with Helicobacter pylori infection. PUD occurs due to an imbalance …

Anti HSV-2 activity of Peganum harmala (L.) and isolation of the active compound

R Benzekri, L Bouslama, A Papetti, M Hammami… - Microbial …, 2018 - Elsevier
Genital herpes is a sexually transmitted disease caused by herpes simplex virus type 2
(HSV-2). Nucleoside analogues such as acyclovir (ACV) are the usual therapy for treating …

Peganum spp.: A Comprehensive Review on Bioactivities and Health‐Enhancing Effects and Their Potential for the Formulation of Functional Foods and …

J Sharifi-Rad, C Quispe, J Herrera-Bravo… - Oxidative Medicine …, 2021 - Wiley Online Library
The genus Peganum includes four species widely distributed in warm temperate to
subtropical regions from the Mediterranean to Mongolia as well as certain regions in …

Harmaline and hispidin from Peganum harmala and Inonotus hispidus with binding affinity to Candida rugosa lipase: In silico and in vitro studies

K Benarous, I Bombarda, I Iriepa, I Moraleda… - Bioorganic …, 2015 - Elsevier
The inhibitory effect of phenolic compounds and alkaloids of Inonotus hispidus and
Peganum harmala on Candida rugosa lipase was investigated, also, their antioxidant …

Alkaloids of Peganum harmala: Anticancer biomarkers with promising outcomes

A Jalali, F Dabaghian… - Current pharmaceutical …, 2021 - ingentaconnect.com
Background: Cancer is a serious and growing global health issue worldwide. In the
cancerous cells, the normal cell cycle has been disrupted via a series of irreversible …

Evaluation of Antidiabetic and Antihyperlipidemic Effects of Peganum harmala Seeds in Diabetic Rats

G Komeili, M Hashemi, M Bameri-Niafar - Cholesterol, 2016 - Wiley Online Library
The present study was carried out to investigate the antidiabetic and antihyperlipidemic
properties of hydroalcoholic extract of Peganum harmala in streptozotocin‐induced diabetic …

Antioxidant mechanisms underlying the gastroprotective effect of menthofuran on experimentally induced gastric lesions in rodents

NM Alves, PHM Nunes… - Evidence‐Based …, 2023 - Wiley Online Library
Menthofuran is a monoterpene present in various essential oils derived from species from
Mentha genus, and in Brazil, those species are widely used in treating gastrointestinal and …

[HTML][HTML] Gastroprotective effect of the alkaloid boldine: Involvement of non-protein sulfhydryl groups, prostanoids and reduction on oxidative stress

T Boeing, LNB Mariano, AC Dos Santos… - Chemico-Biological …, 2020 - Elsevier
Boldine is the main alkaloid of Peumus boldus Molina, widely used in the traditional
medicine for the treatment of digestive disorders. It is a compound with excellent antioxidant …

Pyrroloquinolines, imidazoquinolines, and pyrroloquinazolines with a bridgehead nitrogen

F Dumitrascu, F Georgescu, E Georgescu… - Advances in Heterocyclic …, 2019 - Elsevier
This chapter presents recent advances in the chemistry of heterocyclic ring systems with a
nitrogen bridgehead including pyrrolo [1, 2-a] quinoline, imidazo [1, 2-a] quinoline, imidazo …