Cancer stem cells: advances in knowledge and implications for cancer therapy
X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment
M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …
frequently characterized by metastasis. Despite considerable progress in melanoma …
Photocatalytic carbon dots‐triggered pyroptosis for whole cancer cell vaccines
Manufacturing whole cancer cell vaccines (WCCV) with both biosafety and efficacy is crucial
for tumor immunotherapy. Pyroptotic cancer cells, due to their highly immunogenic …
for tumor immunotherapy. Pyroptotic cancer cells, due to their highly immunogenic …
Quality by design (QbD) assisted Fabrication & evaluation of Simvastatin loaded Nano-Enabled thermogel for melanoma therapy
Melanoma is a form of skin cancer that starts in melanocytes. Rampant chemo-resistance,
metastasis, and inability to cross the skin barriers and accumulate within the tumor …
metastasis, and inability to cross the skin barriers and accumulate within the tumor …
Quality by design steered development of Niclosamide loaded liposomal thermogel for Melanoma: In vitro and Ex vivo evaluation
Melanoma is the most malignant form of skin cancer across the globe. Conventional
therapies are currently ineffective which could be attributed to the rampant chemo …
therapies are currently ineffective which could be attributed to the rampant chemo …
Heterogeneity in melanoma
Simple Summary Tumour heterogeneity is a phenomenon where the cancer cells evolve
diversely over the course of the disease. As a result of the evolution, the cancer cells can be …
diversely over the course of the disease. As a result of the evolution, the cancer cells can be …
Advances in adoptive T-cell therapy for metastatic melanoma
A Das, A Ghose, K Naicker, E Sanchez… - Current Research in …, 2023 - Elsevier
Adoptive T cell therapy (ACT) is a fast developing, niche area of immunotherapy (IO), which
is revolutionising the therapeutic landscape of solid tumour oncology, especially metastatic …
is revolutionising the therapeutic landscape of solid tumour oncology, especially metastatic …
Oxygen‐generating cryogels restore T cell mediated cytotoxicity in hypoxic tumors
T Colombani, LJ Eggermont, SM Hatfield… - Advanced functional …, 2021 - Wiley Online Library
Solid tumors are protected from antitumor immune responses due to their hypoxic
microenvironments. Weakening hypoxia‐driven immunosuppression by hyperoxic breathing …
microenvironments. Weakening hypoxia‐driven immunosuppression by hyperoxic breathing …
Can CD133 Be Regarded as a Prognostic Biomarker in Oncology: Pros and Cons
A Gisina, Y Kim, K Yarygin, A Lupatov - International Journal of Molecular …, 2023 - mdpi.com
The CD133 cell membrane glycoprotein, also termed prominin-1, is expressed on some of
the tumor cells of both solid and blood malignancies. The CD133-positive tumor cells were …
the tumor cells of both solid and blood malignancies. The CD133-positive tumor cells were …
Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in health and disease
P Pleskač, CA Fargeas, R Veselska, D Corbeil… - Cellular & Molecular …, 2024 - Springer
Abstract Prominin-1 (CD133) is a cholesterol-binding membrane glycoprotein selectively
associated with highly curved and prominent membrane structures. It is widely recognized …
associated with highly curved and prominent membrane structures. It is widely recognized …