The term osteoarthritis describes a common, age-related, heterogeneous group of disorders
characterised pathologically by focal areas of loss of articular cartilage in synovial joints …

Although the multifactorial nature of osteoarthritis (OA) is well recognized, genetic factors
have been found to be strong determinants of the disease. Evidence of a genetic influence …

BACKGROUND: Osteoarthritis is the most common form of arthritis worldwide and is a major
cause of pain and disability in elderly people. The health economic burden of osteoarthritis …

Two-hundred and sixty-nine shoulders in 223 patients with a diagnosis of primary frozen
shoulder were studied. The main outcome measure was the Oxford shoulder score. The …

Osteoarthritis (OA) has a considerable hereditary component and is considered to be a
polygenic disease. Data derived from genetic analyses and genome-wide screening of …

Osteoarthritis is a prevalent and disabling disease affecting an increasingly large swathe of
the world population. While clinical osteoarthritis is a late-stage condition for which disease …

Purpose Early OA primarily affects articular cartilage and involves the entire joint, including
the subchondral bone, synovial membrane, menisci and periarticular structures. The aim of …

Osteoarthritis (OA) is the most common cause of arthritis and represents an enormous
healthcare burden in industrialized societies. Current therapeutic approaches for OA are …

Osteoarthritis (OA) is the most prevalent form of arthritis in the elderly. A large body of
evidence, including familial aggregation and classic twin studies, indicates that primary OA …

Osteoarthritis (OA) is the most common form of arthritis and the major cause of activity
limitation and physical disability in older people. Today, 35 million people (13 percent of the …