Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a
neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK …

Histiocytic neoplasms, a rare and heterogeneous group of disorders, primarily include
Erdheim-Chester disease, Langerhans cell histiocytosis, and Rosai-Dorfman disease. Due …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Histiocytoses are heterogeneous hematopoietic diseases characterized by the accumulation
of CD68 (+) cells with various admixed inflammatory infiltrates. The identification of the …

Erdheim–Chester disease (ECD) is a rare non-Langerhans cell histiocytosis with a putative
neoplastic and inflammatory nature. The disease is driven by mutations in proto-oncogenes …

Spontaneous intracranial hypotension is a condition characterized by low CSF volume
secondary to leakage through a dural defect with no identifiable cause. Patients classically …

Abstract Background Erdheim–Chester disease (ECD) is a rare histiocytic neoplasm
characterized by recurrent alterations in the MAPK (mitogen-activating protein kinase) …

Erdheim–Chester disease (ECD) is a rare but increasingly recognized multi-system
disorder. Its diagnosis and treatment require integration of clinical information, imaging …

Objective CNS involvement in Erdheim-Chester disease (ECD) leads to substantial
morbidity and mortality. To assess CNS manifestations in a French cohort of 253 patients …

Erdheim‐Chester disease is a non‐Langerhans cell histiocytosis syndrome characterised by
histiocytic infiltration of different organs and systems in the body. Erdheim‐Chester disease …