Alternative animal models of aging research
S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology
African annual fishes from the genus Nothobranchius are small teleosts that inhabit
temporary water bodies subject to annual desiccation due to the alternation of the monsoon …
temporary water bodies subject to annual desiccation due to the alternation of the monsoon …
Regulation of life span by the gut microbiota in the short-lived African turquoise killifish
Gut bacteria occupy the interface between the organism and the external environment,
contributing to homeostasis and disease. Yet, the causal role of the gut microbiota during …
contributing to homeostasis and disease. Yet, the causal role of the gut microbiota during …
Insights into sex chromosome evolution and aging from the genome of a short-lived fish
The killifish Nothobranchius furzeri is the shortest-lived vertebrate that can be bred in the
laboratory. Its rapid growth, early sexual maturation, fast aging, and arrested embryonic …
laboratory. Its rapid growth, early sexual maturation, fast aging, and arrested embryonic …
[图书][B] Mechanisms of life history evolution: the genetics and physiology of life history traits and trade-offs
Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate
Resveratrol, a natural phytoalexin found in grapes and red wine [1], increases longevity in
the short-lived invertebrates Caenorhabditis elegans and Drosophila [2–5] and exerts a …
the short-lived invertebrates Caenorhabditis elegans and Drosophila [2–5] and exerts a …
[HTML][HTML] A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate
Aging is a complex process that affects multiple organs. Modeling aging and age-related
diseases in the lab is challenging because classical vertebrate models have relatively long …
diseases in the lab is challenging because classical vertebrate models have relatively long …
RNA‐seq of the aging brain in the short‐lived fish N. furzeri – conserved pathways and novel genes associated with neurogenesis
The brains of teleost fish show extensive adult neurogenesis and neuronal regeneration.
The patterns of gene regulation during fish brain aging are unknown. The short‐lived teleost …
The patterns of gene regulation during fish brain aging are unknown. The short‐lived teleost …
The evolution of an annual life cycle in killifish: adaptation to ephemeral aquatic environments through embryonic diapause
AI Furness - Biological Reviews, 2016 - Wiley Online Library
An annual life cycle is characterized by growth, maturity, and reproduction condensed into a
single, short season favourable to development, with production of embryos (seeds, cysts, or …
single, short season favourable to development, with production of embryos (seeds, cysts, or …
Laboratory breeding of the short-lived annual killifish Nothobranchius furzeri
M Polačik, R Blažek, M Reichard - Nature Protocols, 2016 - nature.com
Turquoise killifish, Nothobranchius furzeri, have an intrinsically short life span, with a median
life span of< 6 months and a maximum (90%) life span of 9 months. This short life span …
life span of< 6 months and a maximum (90%) life span of 9 months. This short life span …