The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Quinazolinones belong to a family of heterocyclic nitrogen compounds that have attracted
increasing interest because of their broad spectrum of biological functions. This review …

The quinazolinone nucleus represents, among the class of fused heterocycles, a very
important scaffold to obtain molecules with biological activities. A review of literature …

Abstract Novel Schiff bases of 1-(2-Aminoethyl) piperidine-3-carboxylic acid were
synthesized, characterized and screened for anticonvulsant activity. Compounds were …

A process for the electrochemical direct C–H arylation of quinazolinones and aryl
tetrafluoroborate diazonium salts with ionic liquid [EMIM] BF4 (1-ethyl-3-methylimidazolium …

Direct activation of sp2 C–H bonds by a palladium catalyst has received significant attention
in organic chemistry. However, most of these C–H activation reactions are carried out in …

In our present work, some novel substituted 4-phenyl-5-vinylpyrrolidin-2-one derivatives
were designed, synthesized, and evaluated for their γ-aminobutyric acid-aminotransferase …

Some new 3-substituted quinazolinones were synthesized and evaluated as inhibitors of
kinases involved in fibrogenic process. The compounds were tested against a panel of both …

A new series of 2, 3‐disubstituted quinazolin‐4 (3H)‐one derivatives bearing triazole and
thiadiazole nucleus has been synthesized and then screened for their urease inhibition …

A simple method to synthesize N-heteropolycyclic quinazolinones was developed including
Knoevenagel condensation of quinazolines and aldehydes and Friedel–Craft alkylation as …