Adipsin is an adipokine predominantly synthesized in adipose tissues and released into
circulation. It is also known as complement factor-D (CFD), acting as the rate-limiting factor …

Worldwide obesity is increasing at an alarming rate in children and adolescents, with the
consequent emergence of co-morbidities. Moreover, the maternal environment during …

Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

Preeclampsia is still the leading cause of morbidity and mortality in pregnancy without a
cure. There are two phenotypes of preeclampsia, early-onset (EOPE) and late-onset (LOPE) …

In the genesis and progression of cardiovascular and metabolic diseases (CVMDs), adipose
tissue plays a pivotal and dual role. Complement factor D (CFD, also known as adipsin) …

Adipokines are peptides, secreted by adipocytes and other cell types with targets in other
tissues, participating in a complex network of humoral factors involved in obesity, insulin …

Pregnancy is a physiologically stressful condition that generates a series of functional
adaptations by the cardiovascular system. The impact of pregnancy on this system persists …

The complement system (C) is a crucial component of the innate immune system. An
increasing body of research has progressively shed light on the pivotal role of C in …

Background Preeclampsia represents a major pregnancy complication, associated with high
rates of perinatal morbidity. The aim of this systematic review is to accumulate current …

Objective The concentrations of complement proteins (adipsin, C3a, and C5a) and soluble
endoglin (sENG) in the plasma were measured in this study, and their value as early …