[HTML][HTML] Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Vascular endothelial cells and innate immunity

Y Shao, J Saredy, WY Yang, Y Sun, Y Lu… - … , and vascular biology, 2020 - Am Heart Assoc
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

FAM69C functions as a kinase for eIF2α and promotes stress granule assembly

Z Wu, F Mei, Y Gan, A Liu, J Hu, Y Jin, Y Yin - EMBO reports, 2023 - embopress.org
Stress granules are dynamic cytoplasmic ribonucleoprotein granules that assemble in
response to cellular stress. Aberrant formation of stress granules has been linked to …

[HTML][HTML] Stress granules involved in formation, progression and metastasis of cancer: A scoping review

MR Asadi, D Rahmanpour, MS Moslehian… - Frontiers in cell and …, 2021 - frontiersin.org
The assembly of stress granules (SGs) is a well-known cellular strategy for reducing stress-
related damage and promoting cell survival. SGs have become important players in human …

[HTML][HTML] Liquid–liquid phase separation in cardiovascular diseases

Y Mo, Y Feng, W Huang, N Tan, X Li, M Jie, T Feng… - Cells, 2022 - mdpi.com
Liquid–liquid phase separation (LLPS) is a biochemical process in cells that can drive
proteins, RNA, and other molecules to concentrate into droplets. These droplets do not have …

Stress granules in cancer

MS Song, E Grabocka - Organelles in Disease, 2020 - Springer
The capacity of cells to organize complex biochemical reactions in intracellular space is a
fundamental organizational principle of life. Key to this organization is the …

[HTML][HTML] Stress granules dynamics: benefits in cancer

JI Lee, S Namkoong - BMB reports, 2022 - ncbi.nlm.nih.gov
Stress granules (SGs) are stress-induced subcellular compartments, which carry out a
particular function to cope with stress. These granules protect cells from stress-related …

[HTML][HTML] SARS-CoV-2 and the central nervous system: emerging insights into hemorrhage-associated neurological consequences and therapeutic considerations

J Mitra, M Kodavati, VE Provasek, KS Rao… - Ageing Research …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) continues to impact our lives by causing …

Regulation of RNA granules by FMRP and implications for neurological diseases

A Lai, AN Valdez‐Sinon, GJ Bassell - Traffic, 2020 - Wiley Online Library
RNA granule formation, which can be regulated by RNA‐binding proteins (RBPs) such as
fragile X mental retardation protein (FMRP), acts as a mechanism to control both the …

Apolipoprotein (a)/Lipoprotein(a)‐Induced Oxidative‐Inflammatory α7‐nAChR/p38 MAPK/IL‐6/RhoA‐GTP Signaling Axis and M1 Macrophage Polarization Modulate …

YK Lin, CT Yeh, KT Kuo, IH Fong… - Oxidative Medicine …, 2022 - Wiley Online Library
Objective. Apolipoprotein (a)/lipoprotein (a)(Lp (a)), a major carrier of oxidized
phospholipids, and α7‐nicotinic acetylcholine receptor (α7‐nAChR) may play an important …