Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision

A Iqubal, MK Iqubal, S Sharma, MA Ansari, AK Najmi… - Life sciences, 2019 - Elsevier
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …

Understanding key mechanisms of exercise-induced cardiac protection to mitigate disease: current knowledge and emerging concepts

BC Bernardo, JYY Ooi, KL Weeks… - Physiological …, 2018 - journals.physiology.org
The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …

Anticancer drug-induced cardiotoxicity: insights and pharmacogenetics

A Adhikari, SMB Asdaq, MA Al Hawaj, M Chakraborty… - Pharmaceuticals, 2021 - mdpi.com
The advancement in therapy has provided a dramatic improvement in the rate of recovery
among cancer patients. However, this improved survival is also associated with enhanced …

Structure-function relationships and modifications of cardiac sarcoplasmic reticulum Ca2+-transport

M Nusier, KS Anureet, NS Dhalla - Physiological Research, 2021 - pmc.ncbi.nlm.nih.gov
Sarcoplasmic reticulum (SR) is a specialized tubular network, which not only maintains the
intracellular concentration of Ca2+ at a low level but is also known to release and …

Cyclophosphamide-induced cardiotoxicity

SS Kamel, NA Abdelbaky… - … and Medical Sciences, 2022 - journals.ekb.eg
One of the commonest antitumor drugs is cyclophosphamide (CP). CP that is used in
management of many tumors and autoimmune disease as well as in polychemotherapy …