Chromosomal microarray analysis (CMA) has been used routinely in pediatric and prenatal
genetic diagnosis in clinical practice, but it has rarely been applied to miscarriage analysis …

Recent progress in genetic testing has facilitated obtaining an etiologic diagnosis in children
with developmental delay/intellectual disability (DD/ID) or multiple congenital anomalies …

Background: Chromosomal microarray (CMA) testing is a first-tier test for patients with
developmental delay, autism, or congenital anomalies. It increases diagnostic yield for …

Background Array‐comparative genomic hybridization (array‐CGH) is a widely used
technique to detect copy number variants (CNVs) associated with developmental …

Interventions: The couple finally chose to terminate the pregnancy based on the ultrasonic
multiple malformations and the abnormal SNP array results. Outcomes: The …

Clinical laboratory diagnostic evaluation of the genomes of children with suspected genetic
disorders, including chromosomal microarray and exome sequencing, cannot detect copy …

Background Chromosomal microarray analysis has been shown to be a valuable and cost
effective assay for elucidating copy number variants (CNVs) in children with intellectual …

Background Array-based comparative genomic hybridization has been assumed to be the
first genetic test offered to detect genomic imbalances in patients with unexplained …

OBJECTIVES To evaluate the prevalence of DNA copy number variants (CNVs) detected
with array comparative genomic hybridization (CGH) in fetuses with central nervous system …

Fetal chromosomal abnormalities are a common cause of spontaneous abortion. The
present study investigated the association between fetal chromosomal abnormalities and …