Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance

T Biswas, UN Dwivedi - Protoplasma, 2019 - Springer
The saponins are a diverse class of natural products, with a broad scale distribution across
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …

Antidiabetic Potentials of Momordica charantia: Multiple Mechanisms Behind the Effects

P Chaturvedi - Journal of medicinal food, 2012 - liebertpub.com
Momordica charantia fruits are used as a vegetable in many countries. From time
immemorial, it has also been used for management of diabetes in the Ayurvedic and …

Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome

MA Alam, R Uddin, N Subhan, MM Rahman… - Journal of …, 2015 - Wiley Online Library
Diabetes, obesity, and metabolic syndrome are becoming epidemic both in developed and
developing countries in recent years. Complementary and alternative medicines have been …

Cucurbitane-Type Triterpenoids from the Fruits of Momordica charantia and Their Cancer Chemopreventive Effects

T Akihisa, N Higo, H Tokuda, M Ukiya… - Journal of natural …, 2007 - ACS Publications
Thirteen cucurbitane-type triterpene glycosides, including eight new compounds named
charantosides I (6), II (7), III (10), IV (11), V (12), VI (13), VII (16), and VIII (17), and five known …

Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia

J Chen, R Tian, M Qiu, L Lu, Y Zheng, Z Zhang - Phytochemistry, 2008 - Elsevier
Five cucurbitacins, kuguacins A–E (1–5), together with three known analogues, 3β, 7β, 25-
trihydroxycucurbita-5,(23E)-diene-19-al (6), 3β, 25-dihydroxy-5β, 19-epoxycucurbita-6,(23E) …

Antiprotozoal and cytotoxic screening of 45 plant extracts from Democratic Republic of Congo

GK Mesia, GL Tona, TH Nanga, RK Cimanga… - Journal of …, 2008 - Elsevier
AIM OF THE STUDY:: To evaluate in vitro the antiprotozoal and cytotoxic activies of 80%
methanol extract from 45 medicinal plants collected in Sankuru (Democratic Republic of …

Kuguacins F–S, cucurbitane triterpenoids from Momordica charantia

JC Chen, WQ Liu, L Lu, MH Qiu, YT Zheng, LM Yang… - Phytochemistry, 2009 - Elsevier
Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation
of fourteen cucurbitane triterpenoids, kuguacins F–S (1–14), including two …

A cell-based screening identifies compounds from the stem of Momordica charantia that overcome insulin resistance and activate AMP-activated protein kinase

HL Cheng, HK Huang, CI Chang, CP Tsai… - Journal of Agricultural …, 2008 - ACS Publications
Treatment of insulin resistance is a critical strategy in the prevention and management of
type 2 diabetes. The crude extracts from all parts of Momordica charantia L. have been …

Cucurbitane triterpenoids from Momordica charantia L. and their inhibitory activity against α-glucosidase, α-amylase and protein tyrosine phosphatase 1B (PTP1B)

J Yue, J Xu, J Cao, X Zhang, Y Zhao - Journal of functional foods, 2017 - Elsevier
Momordica charantia L. has been widely used in different countries as a functional food
source, particularly as a remedy for type 2 diabetes. In the present study, 21 cucurbitane …

The triterpenoids of the bitter gourd (Momordica Charantia) and their pharmacological activities: A review

L Sun, X Zhang, L Dong, C Zhang, P Guo… - Journal of Food …, 2021 - Elsevier
The bitter gourd (Momordica charantia L.) is a world-famous medical vegetable involved in
multiple pharmacological activities especially known for its lipid-and glucose-lowering …