DM Walker, S Oghumu, G Gupta, BS McGwire… - Cellular and molecular …, 2014 - Springer
Numerous disease-causing parasites must invade host cells in order to prosper. Collectively, such pathogens are responsible for a staggering amount of human sickness …
Leishmania donovani causes visceral leishmaniasis (VL) where the parasite infects and resides inside liver and spleen tissue macrophages. Given the abnormal lipid profile …
Vector-borne illnesses comprise a significant portion of human maladies, representing 17% of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …
Background Aging is accompanied by increasing vulnerability to pathologies such as atherosclerosis (ATH) and Alzheimer disease (AD). Are these different pathologies, or …
S Rabhi, I Rabhi, B Trentin, D Piquemal, B Regnault… - PLoS …, 2016 - journals.plos.org
Leishmania, the causative agent of vector-borne diseases, known as leishmaniases, is an obligate intracellular parasite within mammalian hosts. The outcome of infection depends …
Two major leishmaniasis treatments have shown a significant decrease in effectiveness in the last few decades, mostly in the Indian subcontinent but also in other endemic areas …
Successful immune responses to pathogens rely on efficient host innate processes to contain and limit bacterial growth, induce inflammatory response and promote antigen …
Y Chen, CM Verfaillie - Liver International, 2014 - Wiley Online Library
Micro RNA s are a class of small non‐coding RNA s involved in the transcriptional and post‐ transcriptional regulation of gene expression. The function of mi RNA s in liver disease …
KR Feingold, C Grunfeld - Journal of lipid research, 2012 - ASBMB
(Of note, hypercholesterolemia increases the mortality of mice infected with M. tuberculosis)(14, 15); e) the utilization of host cholesterol by Toxoplasma gondii for growth …