Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

Numerous disease-causing parasites must invade host cells in order to prosper.
Collectively, such pathogens are responsible for a staggering amount of human sickness …

Leishmania donovani causes visceral leishmaniasis (VL) where the parasite infects and
resides inside liver and spleen tissue macrophages. Given the abnormal lipid profile …

Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Background Aging is accompanied by increasing vulnerability to pathologies such as
atherosclerosis (ATH) and Alzheimer disease (AD). Are these different pathologies, or …

Leishmania, the causative agent of vector-borne diseases, known as leishmaniases, is an
obligate intracellular parasite within mammalian hosts. The outcome of infection depends …

Two major leishmaniasis treatments have shown a significant decrease in effectiveness in
the last few decades, mostly in the Indian subcontinent but also in other endemic areas …

Successful immune responses to pathogens rely on efficient host innate processes to
contain and limit bacterial growth, induce inflammatory response and promote antigen …

Micro RNA s are a class of small non‐coding RNA s involved in the transcriptional and post‐
transcriptional regulation of gene expression. The function of mi RNA s in liver disease …

(Of note, hypercholesterolemia increases the mortality of mice infected with M.
tuberculosis)(14, 15); e) the utilization of host cholesterol by Toxoplasma gondii for growth …