In Silico and Chromatographic Methods for Analysis of Biotransformation of Prospective Neuroprotective Pyrrole-Based Hydrazone in Isolated Rat Hepatocytes
In the current study, chromatographic and in silico techniques were applied to investigate
the biotransformation of ethyl 5-(4-bromophenyl)-1-(2-(2-(2-hydroxybenzylidene) hydrazinyl) …
the biotransformation of ethyl 5-(4-bromophenyl)-1-(2-(2-(2-hydroxybenzylidene) hydrazinyl) …
4‐Furfuryloxymethyl‐1, 2, 3‐triazol‐1‐yl‐acetohydrazide Hybrids as Cholinesterase and Carbonic Anhydrase Inhibitors: Synthesis, Characterization and …
H Şenol - ChemistrySelect, 2024 - Wiley Online Library
This study focused on the synthesis and evaluation of the biological activity of ten novel
acetohydrazide hybrid derivatives, having furfuryloxy‐1, 2, 3‐triazole ring. All the target …
acetohydrazide hybrid derivatives, having furfuryloxy‐1, 2, 3‐triazole ring. All the target …
Metabolic stability of a hydrazone derivative: N′-[(4-chlorophenyl) methylidene)]-4-[(4-methylphenyl) sulfonyloxy] benzohydrazide
Metabolic stability, a key parameter in drug development, refers to a drug substance's
resistance to metabolism. The failure rate can be significantly reduced by conducting …
resistance to metabolism. The failure rate can be significantly reduced by conducting …