Estimating intra-cluster correlation coefficients for planning longitudinal cluster randomized trials: a tutorial
It is well-known that designing a cluster randomized trial (CRT) requires an advance
estimate of the intra-cluster correlation coefficient (ICC). In the case of longitudinal CRTs …
estimate of the intra-cluster correlation coefficient (ICC). In the case of longitudinal CRTs …
Power and sample size analysis for longitudinal mixed models of health in populations exposed to environmental contaminants: a tutorial
Background When evaluating the impact of environmental exposures on human health,
study designs often include a series of repeated measurements. The goal is to determine …
study designs often include a series of repeated measurements. The goal is to determine …
A general method for calculating power for GEE analysis of complete and incomplete stepped wedge cluster randomized trials
Stepped wedge designs have uni-directional crossovers at randomly assigned time points
(steps) where clusters switch from control to intervention condition. Incomplete stepped …
(steps) where clusters switch from control to intervention condition. Incomplete stepped …
The staircase cluster randomised trial design: A pragmatic alternative to the stepped wedge
This article introduces the 'staircase'design, derived from the zigzag pattern of steps along
the diagonal of a stepped wedge design schematic where clusters switch from control to …
the diagonal of a stepped wedge design schematic where clusters switch from control to …
Does it decay? Obtaining decaying correlation parameter values from previously analysed cluster randomised trials
A frequently applied assumption in the analysis of data from cluster randomised trials is that
the outcomes from all participants within a cluster are equally correlated. That is, the …
the outcomes from all participants within a cluster are equally correlated. That is, the …
Intravesical Interferon Therapy vs Hyaluronic Acid for Pain Among Female Individuals With Interstitial Cystitis: A Randomized Clinical Trial
S Shen, L Peng, X Zeng, J Zhang, H Shen… - JAMA Network …, 2024 - jamanetwork.com
Importance Interstitial cystitis (IC) is a debilitating condition. Although viral infection is a
potential etiological cause, few studies have detected the effect of antiviral treatment …
potential etiological cause, few studies have detected the effect of antiviral treatment …
Maintaining the validity of inference from linear mixed models in stepped-wedge cluster randomized trials under misspecified random-effects structures
Linear mixed<? show [AQ ID= GQ2 POS=-18pt]?><? show [AQ ID= GQ4]?><? show [AQ ID=
GQ5 POS= 12pt]?> models are commonly used in analyzing stepped-wedge cluster …
GQ5 POS= 12pt]?> models are commonly used in analyzing stepped-wedge cluster …
Planning stepped wedge cluster randomized trials to detect treatment effect heterogeneity
Stepped wedge design is a popular research design that enables a rigorous evaluation of
candidate interventions by using a staggered cluster randomization strategy. While …
candidate interventions by using a staggered cluster randomization strategy. While …
Generalizing the information content for stepped wedge designs: A marginal modeling approach
Stepped wedge trials are increasingly adopted because practical constraints necessitate
staggered roll‐out. While a complete design requires clusters to collect data in all periods …
staggered roll‐out. While a complete design requires clusters to collect data in all periods …
Sample size calculations for stepped wedge designs with treatment effects that may change with the duration of time under intervention
The stepped wedge design is often used to evaluate interventions as they are rolled out
across schools, health clinics, communities, or other clusters. Most models used in the …
across schools, health clinics, communities, or other clusters. Most models used in the …