Regulation of Staphylococcus aureus Virulence

C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …

RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3′UTR required for intermediate vancomycin resistance

DG Mediati, JL Wong, W Gao, S McKellar… - Nature …, 2022 - nature.com
Abstract Treatment of methicillin-resistant Staphylococcus aureus infections is dependent on
the efficacy of last-line antibiotics including vancomycin. Treatment failure is commonly …

SarS is a repressor of Staphylococcus aureus bicomponent pore-forming leukocidins

EE Anderson, S Dyzenhaus, JK Ilmain… - Infection and …, 2023 - Am Soc Microbiol
Staphylococcus aureus is a successful pathogen that produces a wide range of virulence
factors that it uses to subvert and suppress the immune system. These include the …

Glutamine synthetase mRNA releases sRNA from its 3′ UTR to regulate carbon/nitrogen metabolic balance in Enterobacteriaceae

M Miyakoshi, T Morita, A Kobayashi, A Berger… - Elife, 2022 - elifesciences.org
Glutamine synthetase (GS) is the key enzyme of nitrogen assimilation induced under
nitrogen limiting conditions. The carbon skeleton of glutamate and glutamine, 2 …

[HTML][HTML] A novel type I toxin-antitoxin system modulates persister cell formation in Staphylococcus aureus

G Habib, J Zhu, B Sun - International Journal of Medical Microbiology, 2020 - Elsevier
A plethora of toxin-antitoxin systems exist in bacteria and has multilateral roles in bacterial
pathogenesis and virulence. Toxin-antitoxin systems have been involved in persister cell …

Differentiation of ncRNAs from small mRNAs in Escherichia coli O157:H7 EDL933 (EHEC) by combined RNAseq and RIBOseq – ryhB encodes the regulatory RNA …

K Neuhaus, R Landstorfer, S Simon, S Schober… - BMC genomics, 2017 - Springer
Background While NGS allows rapid global detection of transcripts, it remains difficult to
distinguish ncRNAs from short mRNAs. To detect potentially translated RNAs, we developed …

Mutation of gdpS gene induces a viable but non-culturable state in Staphylococcus epidermidis and changes in the global transcriptional profile

T Zhu, W Wang, H Wang, Y Zhao, D Qu, Y Wu - BMC microbiology, 2022 - Springer
Background In the genome of staphylococci, only the gdpS gene encodes the conserved
GGDEF domain, which is the characteristic of diguanylate cyclases. In our previous study …

SarS and Rot are necessary for the repression of lukED and lukSF-PV in Staphylococcus aureus

EE Anderson, JK Ilmain, VJ Torres - Microbiology Spectrum, 2023 - Am Soc Microbiol
Staphylococcus aureus is an opportunistic pathogen that employs an array of different
virulence factors to evade the immune system. The bi-component pore-forming leukocidins …

Molecular Detection of Methicillin-Resistant Staphylococcus aureus by Non-Protein Coding RNA-Mediated Monoplex Polymerase Chain Reaction

CY Soo Yean, K Selva Raju, R Xavier, S Subramaniam… - Plos one, 2016 - journals.plos.org
Non-protein coding RNA (npcRNA) is a functional RNA molecule that is not translated into a
protein. Bacterial npcRNAs are structurally diversified molecules, typically 50–200 …

2015 年中国微生物遗传学研究领域若干重要进展

谢建平, 韩玉波, 刘钢, 白林泉 - 遗传, 2016 - chinagene.cn
中国微生物遗传学研究在2015 年取得了重要进展. 本文回顾了2015 年度中国本土科研团队在
微生物遗传学领域取得的若干重要科研进展, 扼要介绍了若干重点论文, 展示了中国科学家在本 …