Nanomaterials provide enormous opportunities to overcome the limitations of conventional
ocular delivery systems, such as low therapeutic efficacy, side effects due to the systemic …

The human eye contains multiple biomarkers related to various diseases, making electronic
contact lens an ideal non-invasive platform for their diagnosis and treatment. Recent …

Tear secretion is a complex process with the involvement of the main and accessory lacrimal
glands, corneal and conjunctival epithelial cells and the Meibomian glands. The lacrimal …

Cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that plays a crucial
role in various human organs, including the respiratory and digestive systems. Dysfunctional …

Cystic fibrosis (CF), also known as mucoviscidosis, is the most common autosomal
recessive genetic disease in the Caucasian population, with an estimated frequency of 1 …

Purpose: The role of cystic fibrosis transmembrane conductance regulator (CFTR) in
lacrimal gland (LG) function has only recently received some attention, mainly from our …

This article focuses on the mechanisms of cystic fibrosis and the resulting microbial
dysbiosis created through this disease. Through mutations in the CFTR gene, chloride ion …

In conclusion, our results presented here provide new proof of the secretory role of LG ducts
beside their piping function. We demonstrated the functional presence of CFTR and VIP …

In conclusion, our results presented here demonstrate the functional presence of NKCC1 in
rabbit LG duct cells, providing further support that this transporter can be the main route of …

This article discusses common ocular manifestations of cystic fibrosis (CF) and cystic fibrosis
transmembrane conductance regulator-related disorders (CFTR-RD). A structured approach …