The cellular morphology and sub-cellular spatial structure critically influence the function of
microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial …

Automated microscopy has given researchers access to great amounts of live cell imaging
data from in vitro and in vivo experiments. Much focus has been put on extracting cell tracks …

The 2019 novel coronavirus, SARS-CoV-2, is a pathogen of critical significance to
international public health. Knowledge of the interplay between molecular-scale virus …

Mast cells (MCs) and dendritic cells (DCs) are essential innate sentinels populating host-
environment interfaces. Using longitudinal intravital multiphoton microscopy of …

To efficiently exploit the potential of several millions of droplets that can be considered as
individual bioreactors in microfluidic experiments, methods to encode different experimental …

Virus spreading in tissues is determined by virus transport, virus multiplication in host cells
and the virus-induced immune response. Cytotoxic T cells remove infected cells with a rate …

Cell migration involves dynamic changes in cell shape. Intricate patterns of cell shape can
be analyzed and classified using advanced shape descriptors, including spherical …

Invasive pulmonary aspergillosis is associated with a high mortality rate and poses a direct
threat to immunocompromised patients. Here, we present the invasive aspergillosis-on-chip …

Neutrophils are amongst the first cells to respond to inflammation and infection. Although
they play a key role in limiting the dissemination of pathogens, the study of their dynamic …

Quantitative imaging in life sciences has evolved into a powerful approach combining
advanced microscopy acquisition and automated analysis of image data. The focus of the …