Susceptibility to HIV infection and AIDS progression is variable among individuals and
populations, and in part genetically determined. Genetic variants of genes encoding HIV co …

Chemokines and chemokine receptors play a crucial role in the trafficking of leukocyte
populations across the body, and are involved in the development of a large variety of …

In this study we investigated the possible role of two CCR5 gene polymorphisms, CCR5Δ32
deletion and CCR5 59029 A→ G promoter point mutation, in determining the susceptibility to …

A review was made in relation to the molecular variability present in North, Central, and
South American Indian populations. It involved results from ancient DNA, mitochondrial DNA …

The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested
for the CCR5delta32 allele, which is known to influence susceptibility to HIV-1 infection. The …

Homozygous sickle cell disease (SCD) has a wide spectrum of clinical manifestations. In
Brazil, the main cause of death of individuals with SCD is recurrent infection. The …

The history of the CCR5 gene as a lens through which to view such issues as intellectual
property, Big Pharma, personalized medicine, and race and genomics. In The Genealogy of …

The CCR5 is a chemokine receptor widely expressed by several immune cells that are
engaged in inflammatory responses. Some populations have individuals exhibiting a 32 bp …

OBJECTIVE:: In the present study, we determined the frequency of Δ32 allele distribution
and its relationship with various carcinomas in a Turkish population. DESIGN AND …