Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
Implications of subclinical tuberculosis for vaccine trial design and global effect
GJ Churchyard, RMGJ Houben, K Fielding… - The Lancet …, 2024 - thelancet.com
Tuberculosis is a leading cause of death from an infectious agent globally. Infectious
subclinical tuberculosis accounts for almost half of all tuberculosis cases in national …
subclinical tuberculosis accounts for almost half of all tuberculosis cases in national …
Aerosolization of viable Mycobacterium tuberculosis bacilli by tuberculosis clinic attendees independent of sputum-Xpert Ultra status
Potential Mycobacterium tuberculosis (Mtb) transmission during different pulmonary
tuberculosis (TB) disease states is poorly understood. We quantified viable aerosolized Mtb …
tuberculosis (TB) disease states is poorly understood. We quantified viable aerosolized Mtb …
International consensus classification of early tuberculosis states to guide research for improved care and prevention: A Delphi exercise
AK Coussens, SMA Zaidi, BA Allwood… - The Lancet …, 2024 - pmc.ncbi.nlm.nih.gov
The current active/latent paradigm of tuberculosis (TB) largely neglects the documented
spectrum of disease. Lack of consistency on definitions, terminology and diagnostic criteria …
spectrum of disease. Lack of consistency on definitions, terminology and diagnostic criteria …
PET-CT outcomes from a randomised controlled trial of rosuvastatin as an adjunct to standard tuberculosis treatment
GB Cross, IP Sari, SM Burkill, CW Yap… - Nature …, 2024 - nature.com
Adjunctive rosuvastatin for rifampicin-susceptible pulmonary tuberculosis (rs-PTB) shows no
effect on microbiological or radiological outcomes in a phase IIb randomised, controlled trial …
effect on microbiological or radiological outcomes in a phase IIb randomised, controlled trial …
Diagnostic Accuracy of Chest X-ray Computer-Aided Detection Software for Detection of Prevalent and Incident Tuberculosis in Household Contacts
L Macpherson, SV Kik, M Quartagno… - Clinical Infectious …, 2024 - academic.oup.com
Abstract Background World Health Organization (WHO) tuberculosis (TB) screening
guidelines recommend computer-aided detection (CAD) software for chest radiograph …
guidelines recommend computer-aided detection (CAD) software for chest radiograph …
[HTML][HTML] Chest Radiograph Screening for Detecting Subclinical Tuberculosis in Asymptomatic Household Contacts, Peru
Abstract The World Health Organization's end TB strategy promotes the use of symptom and
chest radiograph screening for tuberculosis (TB) disease. However, asymptomatic early …
chest radiograph screening for tuberculosis (TB) disease. However, asymptomatic early …
Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa
T Tamuhla, AK Coussens… - Wellcome Open …, 2025 - wellcomeopenresearch.org
Background There is limited knowledge regarding African genetic drivers of disease due to
prohibitive costs of large-scale genomic research in Africa. Methods We piloted a scalable …
prohibitive costs of large-scale genomic research in Africa. Methods We piloted a scalable …
[HTML][HTML] Mathematical modeling suggests heterogeneous replication of Mycobacterium tuberculosis in rabbits
Tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb), remains a
major health problem with 10.6 million cases of the disease and 1.6 million deaths in 2021. It …
major health problem with 10.6 million cases of the disease and 1.6 million deaths in 2021. It …
Imaging in early tuberculosis
R Wilkinson - Thorax, 2024 - thorax.bmj.com
Tuberculosis (TB) is a pressing global human health problem that resulted in over 10 million
cases and 1.3 million deaths in 2022. 1 The WHO proposes to end this global epidemic by …
cases and 1.3 million deaths in 2022. 1 The WHO proposes to end this global epidemic by …