Nanocrystals of poorly soluble drugs: drug bioavailability and physicochemical stability

MR Gigliobianco, C Casadidio, R Censi, P Di Martino - Pharmaceutics, 2018 - mdpi.com
Many approaches have been developed over time to overcome the bioavailability limitations
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …

Physical and chemical stability of drug nanoparticles

L Wu, J Zhang, W Watanabe - Advanced drug delivery reviews, 2011 - Elsevier
As nano-sizing is becoming a more common approach for pharmaceutical product
development, researchers are taking advantage of the unique inherent properties of …

Methods for characterization of nanoparticles

A Kumar, CK Dixit - Advances in nanomedicine for the delivery of …, 2017 - Elsevier
Nanoparticle manufacturing industries use well-established synthesis protocols or
methodology as much as possible. The nanomaterials have unique physical and chemical …

Electrospraying of polymers with therapeutic molecules: State of the art

N Bock, TR Dargaville, MA Woodruff - Progress in polymer science, 2012 - Elsevier
The encapsulation and release of bioactive molecules from polymeric vehicles represents
the holy grail of drug and growth factor delivery therapies, whereby sustained and controlled …

Electrohydrodynamic atomization: A two-decade effort to produce and process micro-/nanoparticulate materials

J Xie, J Jiang, P Davoodi, MP Srinivasan… - Chemical engineering …, 2015 - Elsevier
Electrohydrodynamic atomization (EHDA), also called electrospray technique, has been
studied for more than one century. However, since 1990s it has begun to be used to produce …

Electrospraying route to nanotechnology: An overview

A Jaworek, AT Sobczyk - Journal of electrostatics, 2008 - Elsevier
Electrospraying (electrohydrodynamic spraying) is a method of liquid atomization by means
of electrical forces. In electrospraying, the liquid at the outlet of a nozzle is subjected to an …

Production methods for nanodrug particles using the bottom-up approach

HK Chan, PCL Kwok - Advanced drug delivery reviews, 2011 - Elsevier
This review focuses on bottom-up processes such as precipitation (or crystallisation) and
single droplet evaporation to produce nanoparticles containing largely pure therapeutics for …

Pharmaceutical applications of electrospraying

DN Nguyen, C Clasen, G Van den Mooter - Journal of pharmaceutical …, 2016 - Elsevier
The electrohydrodynamic atomization technique, or simply called electrospraying, has been
extensively studied for biomedical as well as for pharmaceutical applications over the past …

Protein nanoparticles: uniting the power of proteins with engineering design approaches

N Habibi, A Mauser, Y Ko, J Lahann - Advanced Science, 2022 - Wiley Online Library
Protein nanoparticles, PNPs, have played a long‐standing role in food and industrial
applications. More recently, their potential in nanomedicine has been more widely pursued …

Drug delivery vehicles on a nano-engineering perspective

B Felice, MP Prabhakaran, AP Rodriguez… - Materials Science and …, 2014 - Elsevier
Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical
tools for not only modulation of pharmacological drug release profile but also specific …