An overview of triple-negative breast cancer

P Kumar, R Aggarwal - Archives of gynecology and obstetrics, 2016 - Springer
Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …

[HTML][HTML] The fate of chemoresistance in triple negative breast cancer (TNBC)

EA O'Reilly, L Gubbins, S Sharma, R Tully, MHZ Guang… - BBA clinical, 2015 - Elsevier
Background Treatment options for women presenting with triple negative breast cancer
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …

Acidity generated by the tumor microenvironment drives local invasion

V Estrella, T Chen, M Lloyd, J Wojtkowiak, HH Cornnell… - Cancer research, 2013 - AACR
The pH of solid tumors is acidic due to increased fermentative metabolism and poor
perfusion. It has been hypothesized that acid pH promotes local invasive growth and …

[HTML][HTML] Triple-negative breast cancer—current status and future directions

O Gluz, C Liedtke, N Gottschalk, L Pusztai, U Nitz… - Annals of …, 2009 - Elsevier
Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen
and progesterone receptor as well as human epidermal growth factor receptor 2. It is …

Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer

AJ Walsh, RS Cook, HC Manning, DJ Hicks… - Cancer research, 2013 - AACR
Abnormal cellular metabolism is a hallmark of cancer, yet there is an absence of quantitative
methods to dynamically image this powerful cellular function. Optical metabolic imaging …

Correlation of high 18F-FDG uptake to clinical, pathological and biological prognostic factors in breast cancer

D Groheux, S Giacchetti, JL Moretti, R Porcher… - European journal of …, 2011 - Springer
Purpose The aim of this study was to determine the impact of the main clinicopathological
and biological prognostic factors of breast cancer on 18 F-fluorodeoxyglucose (FDG) uptake …

[PDF][PDF] Molecular classification of breast cancer

E Provenzano, GA Ulaner, SF Chin - PET clinics, 2018 - Elsevier
Molecular Classification of Breast Cancer Page 1 1 | Page ARTICLE TITLE Molecular
Classification Of Breast Cancer AUTHOR NAMES AND DEGREES Elena Provenzano MBBS …

Progress and future trends in PET/CT and PET/MRI molecular imaging approaches for breast cancer

Y Ming, N Wu, T Qian, X Li, DQ Wan, C Li, Y Li… - Frontiers in …, 2020 - frontiersin.org
Breast cancer is a major disease with high morbidity and mortality in women worldwide.
Increased use of imaging biomarkers has been shown to add more information with clinical …

[HTML][HTML] Triple-negative breast cancer: present challenges and new perspectives

F Podo, LMC Buydens, H Degani, R Hilhorst, E Klipp… - Molecular …, 2010 - Elsevier
Triple-negative breast cancers (TNBC), characterized by absence of estrogen receptor (ER),
progesterone receptor (PR) and lack of overexpression of human epidermal growth factor …

Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential

H Pelicano, W Zhang, J Liu, N Hammoudi, J Dai… - Breast cancer …, 2014 - Springer
Introduction Triple-negative breast cancer (TNBC) is a subtype of highly malignant breast
cancer with poor prognosis. TNBC is not amenable to endocrine therapy and often exhibit …