[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

J Sharifi-Rad, C Quispe, CMS Castillo… - Oxidative medicine …, 2022 - Wiley Online Library
Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

[HTML][HTML] Dietary polyphenol, gut microbiota, and health benefits

X Wang, Y Qi, H Zheng - Antioxidants, 2022 - mdpi.com
Polyphenols, which are probably the most important secondary metabolites produced by
plants, have attracted tremendous attention due to their health-promoting effects, including …

[HTML][HTML] Regulation of intestinal barrier function by microbial metabolites

S Ghosh, CS Whitley, B Haribabu, VR Jala - Cellular and molecular …, 2021 - Elsevier
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

[HTML][HTML] Impact of the natural compound urolithin A on health, disease, and aging

D D'Amico, PA Andreux, P Valdés, A Singh… - Trends in molecular …, 2021 - cell.com
Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate …

[HTML][HTML] The interactions between polyphenols and microorganisms, especially gut microbiota

M Makarewicz, I Drożdż, T Tarko, A Duda-Chodak - Antioxidants, 2021 - mdpi.com
This review presents the comprehensive knowledge about the bidirectional relationship
between polyphenols and the gut microbiome. The first part is related to polyphenols' …

[HTML][HTML] Role of the encapsulation in bioavailability of phenolic compounds

J Grgić, G Šelo, M Planinić, M Tišma, A Bucić-Kojić - Antioxidants, 2020 - mdpi.com
Plant-derived phenolic compounds have multiple positive health effects for humans
attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc. These …

[HTML][HTML] Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

R Singh, S Chandrashekharappa, SR Bodduluri… - Nature …, 2019 - nature.com
The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …

[HTML][HTML] Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

D Denk, V Petrocelli, C Conche, M Drachsler… - Immunity, 2022 - cell.com
T memory stem cells (T SCM) display increased self-renewal and prolonged survival
capabilities, thus preventing T cell exhaustion and promoting effective anti-tumor T cell …

Urolithin A improves mitochondrial health, reduces cartilage degeneration, and alleviates pain in osteoarthritis

D D'Amico, M Olmer, AM Fouassier, P Valdés… - Aging cell, 2022 - Wiley Online Library
Osteoarthritis (OA) is the most common age‐related joint disorder with no effective therapy.
According to the World Health Organization, OA affects over 500 million people and is …

[HTML][HTML] From association to causality: the role of the gut microbiota and its functional products on host metabolism

A Koh, F Bäckhed - Molecular cell, 2020 - cell.com
Many genomic studies have revealed associations between the gut microbiota composition
and host metabolism. These observations led to the idea that a causal relationship could …