Estimating the natural indirect effect and the mediation proportion via the product method

C Cheng, D Spiegelman, F Li - BMC medical research methodology, 2021 - Springer
Background The natural indirect effect (NIE) and mediation proportion (MP) are two
measures of primary interest in mediation analysis. The standard approach for mediation …

An exact regression‐based approach for the estimation of natural direct and indirect effects with a binary outcome and a continuous mediator

M Samoilenko, G Lefebvre - Statistics in Medicine, 2023 - Wiley Online Library
In the causal mediation framework, a number of parametric regression‐based approaches
have been introduced in recent years for estimating natural direct and indirect effects for a …

Is the product method more efficient than the difference method for assessing mediation?

C Cheng, D Spiegelman, F Li - American Journal of …, 2023 - academic.oup.com
Mediation analysis is widely used in biomedical research to quantify the extent to which the
effect from an exposure on a health outcome is through a mediator and the extent to which …

[HTML][HTML] Bayesian joint modeling for causal mediation analysis with a binary outcome and a binary mediator: Exploring the role of obesity in the association between …

M Caubet, M Samoilenko, S Drouin, D Sinnett… - … Statistics & Data …, 2023 - Elsevier
Mediation analysis with a binary outcome is notoriously more challenging than with a
continuous outcome. A new Bayesian approach for performing causal mediation with a …

Sensitivity analysis for unobserved confounding in causal mediation analysis allowing for effect modification, censoring and truncation

A Lindmark - Statistical Methods & Applications, 2022 - Springer
Causal mediation analysis is used to decompose the total effect of an exposure on an
outcome into an indirect effect, taking the path through an intermediate variable, and a direct …

An empirical evaluation of approximate and exact regression-based causal mediation approaches for a binary outcome and a continuous or a binary mediator for case …

M Caubet, K L'Espérance, A Koushik… - BMC Medical Research …, 2024 - Springer
Background In the causal mediation analysis framework, several parametric regression-
based approaches have been introduced in past years for decomposing the total effect of an …

Path analysis for binary random variables

M Raggi, E Stanghellini… - Sociological Methods & …, 2023 - journals.sagepub.com
The decomposition of the overall effect of a treatment into direct and indirect effects is here
investigated with reference to a recursive system of binary random variables. We show how …

The derivative-based approach to nonlinear mediation models: insights and applications

C Di Maria, C Rubino, A Albano - Quality & Quantity, 2024 - Springer
Traditional mediation analysis has been developed in the context of linear models, enabling
the estimation of indirect effects through the product of regression coefficients. However, in …

Mediation analysis with case–control sampling: Identification and estimation in the presence of a binary mediator

M Doretti, M Genbäck, E Stanghellini - Biometrical Journal, 2024 - Wiley Online Library
With reference to a stratified case–control (CC) procedure based on a binary variable of
primary interest, we derive the expression of the distortion induced by the sampling design …

Investigating the Causal Effect of Deforestation on Infant Health Through Soil Characteristics: A Comparison of Traditional and Machine Learning Mediation Analysis …

C Di Maria - Journal of Agricultural, Biological and Environmental …, 2025 - Springer
Deforestation is a global threat that impacts the environment and biodiversity in several
ways. Recently, some scholars started investigating how deforestation affects human health …