The ins and outs of HIV‐1 Tat

S Debaisieux, F Rayne, H Yezid, B Beaumelle - Traffic, 2012 - Wiley Online Library
HIV‐1 encodes for the small basic protein Tat (86–101 residues) that drastically enhances
the efficiency of viral transcription. The mechanism enabling Tat nuclear import is not yet …

Beyond RGD: virus interactions with integrins

HAM Hussein, LR Walker, UM Abdel-Raouf… - Archives of …, 2015 - Springer
Viruses successfully infect host cells by initially binding to the surfaces of the cells, followed
by an intricate entry process. As multifunctional heterodimeric cell-surface receptor …

Functions of Tat: the versatile protein of human immunodeficiency virus type 1

B Romani, S Engelbrecht… - Journal of general …, 2010 - microbiologyresearch.org
Human immunodeficiency virus type 1 (HIV-1) Tat is a multifunctional protein that contributes
to several pathological symptoms of HIV-1 infection as well as playing a critical role in virus …

HIV proteins and endothelial dysfunction: implications in cardiovascular disease

AR Anand, G Rachel, D Parthasarathy - Frontiers in cardiovascular …, 2018 - frontiersin.org
With the success of antiretroviral therapy (ART), a dramatic decrease in viral burden and
opportunistic infections and an increase in life expectancy has been observed in human …

Hedgehog signaling: implications in cancers and viral infections

S Iriana, K Asha, M Repak… - International Journal of …, 2021 - mdpi.com
The hedgehog (SHH) signaling pathway is primarily involved in embryonic gut development,
smooth muscle differentiation, cell proliferation, adult tissue homeostasis, tissue repair …

[HTML][HTML] HIV-associated disruption of mucosal epithelium facilitates paracellular penetration by human papillomavirus

SM Tugizov, R Herrera, P Chin-Hong, P Veluppillai… - Virology, 2013 - Elsevier
The incidence of human papillomavirus (HPV)-associated epithelial lesions is substantially
higher in human immunodeficiency virus (HIV)-infected individuals than in HIV-uninfected …

RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade

S Pleschka - 2008 - degruyter.com
Abstract The Raf/MEK/ERK signal transduction cascade belongs to the mitogen-activated
protein kinase (MAPK) cascades. Raf/MEK/ERK signaling leads to stimulus-specific …

Deciphering the complete human-monkeypox virus interactome: Identifying immune responses and potential drug targets

R Kataria, S Kaur, R Kaundal - Frontiers in Immunology, 2023 - frontiersin.org
Monkeypox virus (MPXV) is a dsDNA virus, belonging to Poxviridae family. The outbreak of
monkeypox disease in humans is critical in European and Western countries, owing to its …

Phosphorylation events during viral infections provide potential therapeutic targets

JA Keating, R Striker - Reviews in medical virology, 2012 - Wiley Online Library
For many medically relevant viruses, there is now considerable evidence that both viral and
cellular kinases play important roles in viral infection. Ultimately, these kinases, and the …

HIV-1 proteins gp120 and tat promote epithelial-mesenchymal transition and invasiveness of HPV-positive and HPV-negative neoplastic genital and oral epithelial …

K Lien, W Mayer, R Herrera, NT Padilla… - Microbiology …, 2022 - Am Soc Microbiol
The incidence of human papillomavirus (HPV)-associated anogenital and oropharyngeal
cancer in human immunodeficiency virus (HIV)-infected individuals is substantially higher …