Homeostasis meets motivation in the battle to control food intake
Signals of energy homeostasis interact closely with neural circuits of motivation to control
food intake. An emerging hypothesis is that the transition to maladaptive feeding behavior …
food intake. An emerging hypothesis is that the transition to maladaptive feeding behavior …
Factors modulating the incubation of drug and non-drug craving and their clinical implications
It was suggested in 1986 that cue-induced cocaine craving increases progressively during
early abstinence and remains high during extended periods of time. Clinical evidence now …
early abstinence and remains high during extended periods of time. Clinical evidence now …
Contrasting forms of cocaine-evoked plasticity control components of relapse
Nucleus accumbens neurons serve to integrate information from cortical and limbic regions
to direct behaviour. Addictive drugs are proposed to hijack this system, enabling drug …
to direct behaviour. Addictive drugs are proposed to hijack this system, enabling drug …
Eating 'junk-food'produces rapid and long-lasting increases in NAc CP-AMPA receptors: implications for enhanced cue-induced motivation and food addiction
MF Oginsky, PB Goforth, CW Nobile… - …, 2016 - nature.com
Urges to eat are influenced by stimuli in the environment that are associated with food (food
cues). Obese people are more sensitive to food cues, reporting stronger craving and …
cues). Obese people are more sensitive to food cues, reporting stronger craving and …
Adolescent maturational transitions in the prefrontal cortex and dopamine signaling as a risk factor for the development of obesity and high fat/high sugar diet induced …
AC Reichelt - Frontiers in behavioral neuroscience, 2016 - frontiersin.org
Adolescence poses as both a transitional period in neurodevelopment and lifestyle
practices. In particular, the developmental trajectory of the prefrontal cortex (PFC), a critical …
practices. In particular, the developmental trajectory of the prefrontal cortex (PFC), a critical …
The central amygdala nucleus is critical for incubation of methamphetamine craving
X Li, T Zeric, S Kambhampati, JM Bossert… - …, 2015 - nature.com
Cue-induced methamphetamine seeking progressively increases after withdrawal but
mechanisms underlying this 'incubation of methamphetamine craving'are unknown. Here we …
mechanisms underlying this 'incubation of methamphetamine craving'are unknown. Here we …
Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving
Relapse represents a consistent clinical problem for individuals with substance use
disorder. In the incubation of craving model of persistent craving and relapse, cue-induced …
disorder. In the incubation of craving model of persistent craving and relapse, cue-induced …
Role of central amygdala neuronal ensembles in incubation of nicotine craving
D Funk, K Coen, S Tamadon, BT Hope… - Journal of …, 2016 - Soc Neuroscience
The craving response to smoking-associated cues in humans or to intravenous nicotine-
associated cues in adult rats progressively increases or incubates after withdrawal. Here, we …
associated cues in adult rats progressively increases or incubates after withdrawal. Here, we …
Recent updates on incubation of drug craving: a mini‐review
Cue‐induced drug craving progressively increases after prolonged withdrawal from drug
self‐administration in laboratory animals, a behavioral phenomenon termed 'incubation of …
self‐administration in laboratory animals, a behavioral phenomenon termed 'incubation of …
[HTML][HTML] Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs
RC Derman, CR Ferrario - Neuropharmacology, 2018 - Elsevier
Studies in humans suggest that stronger incentive motivational responses to Pavlovian food
cues may drive over-consumption leading to and maintaining obesity, particularly in …
cues may drive over-consumption leading to and maintaining obesity, particularly in …