Robust T cell responses have been associated with milder outcomes in many infections. T
cells also establish long-term memory pools and, as they are predominantly directed toward …

SARS-CoV-2 mRNA vaccines induce robust anti-spike (S) antibody and CD4+ T cell
responses. It is not yet clear whether vaccine-induced follicular helper CD4+ T (T FH) cell …

Since late 2019 the newly emerged pandemic SARS-CoV-2, the causative agent of COVID-
19, has hit the world with recurring waves of infections necessitating the global …

BACKGROUND The repeated waves of the COVID-19 pandemic have highlighted the
necessity to optimize vaccine responses in immunocompromised populations. We …

Background: Patients affected by different types of autoimmune diseases, including common
conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …

To understand reinfection rates and correlates of protection for severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), we established eight different longitudinal cohorts …

T cells responses are a key cornerstone to viral immunity to drive high quality antibody
responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T …

Background: Multiple sclerosis (MS) is a neurological disorder marked by accumulating
immune-mediated damage to the central nervous system. The dysregulated immune system …

In the past few years, huge advances have been made in techniques to analyse cells at an
individual level using RNA sequencing, and many of these have precipitated exciting …

Human breastmilk is rich in T cells; however, their specificity and function are largely
unknown. We compared the phenotype, diversity, and antigen specificity of T cells in …