SARS-CoV-2 mRNA vaccines induce robust anti-spike (S) antibody and CD4+ T cell responses. It is not yet clear whether vaccine-induced follicular helper CD4+ T (T FH) cell …
F Günl, A Mecate-Zambrano, S Rehländer, S Hinse… - Vaccines, 2021 - mdpi.com
Since late 2019 the newly emerged pandemic SARS-CoV-2, the causative agent of COVID- 19, has hit the world with recurring waves of infections necessitating the global …
Y Peled, E Ram, J Lavee, A Segev, S Matezki… - The Journal of Heart and …, 2022 - Elsevier
BACKGROUND The repeated waves of the COVID-19 pandemic have highlighted the necessity to optimize vaccine responses in immunocompromised populations. We …
NJM Verstegen, RR Hagen, J van den Dijssel… - Elife, 2022 - elifesciences.org
Background: Patients affected by different types of autoimmune diseases, including common conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …
V Simon, V Kota, RF Bloomquist, HB Hanley… - MSphere, 2022 - Am Soc Microbiol
To understand reinfection rates and correlates of protection for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we established eight different longitudinal cohorts …
THO Nguyen, CA Cohen, LC Rowntree, MB Bull… - Frontiers in …, 2021 - frontiersin.org
T cells responses are a key cornerstone to viral immunity to drive high quality antibody responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T …
AT Reder, O Stuve, SK Tankou… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: Multiple sclerosis (MS) is a neurological disorder marked by accumulating immune-mediated damage to the central nervous system. The dysregulated immune system …
SJ Hanna, D Tatovic, TC Thayer… - Frontiers in immunology, 2021 - frontiersin.org
In the past few years, huge advances have been made in techniques to analyse cells at an individual level using RNA sequencing, and many of these have precipitated exciting …
B Armistead, Y Jiang, M Carlson, ES Ford, S Jani… - Mucosal …, 2023 - Elsevier
Human breastmilk is rich in T cells; however, their specificity and function are largely unknown. We compared the phenotype, diversity, and antigen specificity of T cells in …