Cerebral hemorrhage: pathophysiology, treatment, and future directions

J Magid-Bernstein, R Girard, S Polster… - Circulation …, 2022 - Am Heart Assoc
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

Y Inoue, F Shue, G Bu, T Kanekiyo - Molecular neurodegeneration, 2023 - Springer
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022 - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

Amyloid-related imaging abnormalities in 2 phase 3 studies evaluating aducanumab in patients with early Alzheimer disease

S Salloway, S Chalkias, F Barkhof, P Burkett… - JAMA …, 2022 - jamanetwork.com
Importance The EMERGE and ENGAGE phase 3 randomized clinical trials of aducanumab
provide a robust data set to characterize amyloid-related imaging abnormalities (ARIA) that …

Intracerebral haemorrhage: current approaches to acute management

C Cordonnier, A Demchuk, W Ziai, CS Anderson - The Lancet, 2018 - thelancet.com
Acute spontaneous intracerebral haemorrhage is a life-threatening illness of global
importance, with a poor prognosis and few proven treatments. As a heterogeneous disease …

Diagnosis of cerebral amyloid angiopathy: evolution of the Boston criteria

SM Greenberg, A Charidimou - Stroke, 2018 - Am Heart Assoc
492 Stroke February 2018 lobar hemorrhages required for probable CAA, or alternatively
preclude probable CAA if in deep territories. The rationale for counting all types of …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

Intracerebral hemorrhage: an update on diagnosis and treatment

IC Hostettler, DJ Seiffge, DJ Werring - Expert review of …, 2019 - Taylor & Francis
Introduction: Spontaneous non-traumatic intracerebral hemorrhage (ICH) is most often
caused by small vessel diseases: deep perforator arteriopathy (hypertensive arteriopathy) or …

Emerging concepts in sporadic cerebral amyloid angiopathy

A Charidimou, G Boulouis, ME Gurol, C Ayata… - Brain, 2017 - academic.oup.com
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

Prevalence of cerebral amyloid angiopathy: a systematic review and meta‐analysis

L Jäkel, AM De Kort, CJM Klijn… - Alzheimer's & …, 2022 - Wiley Online Library
Reported prevalence estimates of sporadic cerebral amyloid angiopathy (CAA) vary widely.
CAA is associated with cognitive dysfunction and intracerebral hemorrhage, and linked to …