PURPOSE OF REVIEW Early-onset Alzheimer disease (AD) is defined as having an age of onset younger than 65 years. While early-onset AD is often overshadowed by the more …
S Hendriks, K Peetoom, C Bakker… - JAMA …, 2021 - jamanetwork.com
Importance Reliable prevalence estimates are lacking for young-onset dementia (YOD), in which symptoms of dementia start before the age of 65 years. Such estimates are needed for …
CAC Coupland, T Hill, T Dening, R Morriss… - JAMA internal …, 2019 - jamanetwork.com
Importance Anticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of …
Alzheimer's disease is largely the underlying cause of dementia due to its progressive neurodegenerative nature among the elderly. The disease can be divided into five stages …
Alzheimer disease (AD) originally meant a disorder of early-onset (EOAD;< 65 years of age) and did not include older patients with “senile dementia.” In fact, the first patient reported …
This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of …
S Hendriks, JM Ranson, K Peetoom, I Lourida… - JAMA …, 2024 - jamanetwork.com
Importance There is limited information on modifiable risk factors for young-onset dementia (YOD). Objective To examine factors that are associated with the incidence of YOD. Design …
In the absence of disease modifying therapies for dementia, the question rises what the benefits are of an early dementia diagnosis for patients and their caregivers. This paper …
Objective The objective of this study is to identify factors determining the time to diagnosis for young‐onset dementia (YOD), defined as dementia with symptom onset before age 65 …