Population stratification (PS) is a primary consideration in studies of genetic determinants of
human traits. Failure to control for PS may lead to confounding, causing a study to fail for …

The 22 Arab nations have a unique genetic structure, which reflects both conserved and
diverse gene pools due to the prevalent endogamous and consanguineous marriage culture …

Background High sequence identity between segmental duplications (SDs) can facilitate
copy number variants (CNVs) via non-allelic homologous recombination (NAHR). These …

With high consanguinity rates on the Arabian Peninsula, it would not have been unexpected
if the population of the United Arab Emirates (UAE) was shown to be relatively homogenous …

The ethnic composition of the population of a country contributes to the uniqueness of each
national DNA sequencing project and, ideally, individual reference genomes are required to …

Abstract Whole Genome Sequencing (WGS) provides an in depth description of genome
variation. In the era of large-scale population genome projects, the assembly of ethnic …

PBX1 is a highly conserved atypical homeodomain transcription factor (TF) belonging to the
TALE (three amino acid loop extension) family. Dimerized with other TALE proteins, it can …

The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman,
Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage …

Objective: The aim of this study was to assess the HLA haplotype frequencies and genetic
profiles of the Kuwaiti population. Materials and Methods: Whole venous blood was …

Introduction: HLA typing is a critical tool in both clinical and research applications at the
individual and population levels. Benchmarking studies have indicated HLA-HD as the …