Uses of viral vectors have thus far eclipsed uses of non-viral vectors for gene therapy
delivery in the clinic. Viral vectors, however, have certain issues involving genome …

In the two decades since their initial discovery, DNA vaccines technologies have come a
long way. Unfortunately, when applied to human subjects inadequate immunogenicity is still …

ABSTRACT A major advantage of DNA vaccination is the ability to induce both humoral and
cellular immune responses. DNA vaccines are currently used in veterinary medicine, but …

Despite advancements in immunotherapeutic approaches, influenza continues to cause
severe illness, particularly among immunocompromised individuals, young children, and …

The challenges of effective vaccination against influenza are gaining more mainstream
attention, as recent influenza seasons have reported low efficacy in annual vaccination …

COVID-19 has caused a global pandemic and millions of deaths. It is imperative to develop
effective countermeasures against the causative viral agent, SARS-CoV-2 and its many …

The cell and gene therapy industry has employed the same plasmid technology for decades
in vaccination, cell and gene therapy, and as a raw material in viral vector and RNA …

The ongoing SARS-CoV-2 pandemic has highlighted both the importance of One Health, ie,
the interactions and transmission of pathogens between animals and humans, and the …

DNA vaccination can be applied to the treatment of various infectious diseases and cancers;
however, technical difficulties have hindered the development of an effective delivery …

Swine influenza virus (SIVs) infections cause a significant economic impact to the pork
industry. Moreover, pigs may act as mixing vessel favoring genome reassortment of diverse …