In recent years mounting problems related to antibiotic‐resistant bacteria have resulted in
the prediction that we are entering the preantibiotic era. A way of preventing such a …

The recent and dramatic rise of antibiotic resistance among bacterial pathogens underlies
the fear that standard treatments for infectious disease will soon be largely ineffective …

The type III secretion system (T3SS) is a virulence apparatus used by many Gram-negative
pathogenic bacteria to cause infections. Pathogens utilizing a T3SS are responsible for …

Understanding the coevolution between humans and our microbial symbionts and
pathogens requires complementary approaches, ranging from community analysis to in …

Society faces huge challenges, as a large number of bacteria have developed resistance
towards many or all of the antibiotics currently available. Novel strategies that can help solve …

A class of anti-virulence compounds, the salicylidene acylhydrazides, has been widely
reported to block the function of the type three secretion system of several Gram-negative …

Bacterial virulence factors have been increasingly regarded as attractive targets for
development of novel antibacterial agents. Virulence inhibitors are less likely to generate …

Salicylanilides have been a subject of interest in medicinal chemistry as a group with a wide
range of biological activities. The antibacterial (including antimycobacterial) and antifungal …

The gut microbiome is comprised of various types of bacteria, fungi, protozoa, and viruses
naturally occurring in humans and animals as normal microflora. Gut microorganisms are …

Introduction: Causative agents of pneumonia, gastroenteritis, typhoid fever, and plague all
utilize a type III secretion system (T3SS) to directly inject proteins into human cells and …