[HTML][HTML] Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration

A Atwal, TP Dale, M Snow, NR Forsyth… - Advances in colloid and …, 2023 - Elsevier
The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed
significant challenges for healthcare practitioners, researchers, and individuals suffering …

Injectable hydrogels as promising in situ therapeutic platform for cartilage tissue engineering

R Cai, Y Shan, F Du, Z Miao, L Zhu, L Hang… - International Journal of …, 2024 - Elsevier
Injectable hydrogels are gaining prominence as a biocompatible, minimally invasive, and
adaptable platform for cartilage tissue engineering. Commencing with their synthesis, this …

Target-Navigated CBT–Cys “Stapling” Coupled with CRISPR/Cas12a Amplification for the Photoelectrochemical Nucleic Acid Assay

J Zheng, X Wang, H Qin, Y Hou, Q Yang… - Analytical …, 2024 - ACS Publications
Generally, rolling circle amplification (RCA) is based on an enzyme-linked padlock
extension reaction. Herein, rapid linking that utilizes click chemistry for joining sticky ends of …

[HTML][HTML] Engineered mechanical dynamics in biomimetic hydrogel scaffold promotes phenotypic maintenance and cartilage formation of chondrocytes

Y Gao, X Guo, X Wang, D Li, H Tang, W Zhao… - Composites Part B …, 2024 - Elsevier
The dedifferentiation of chondrocytes in cartilage tissue engineering (CTE) remains an
unsolved challenge for the successful repair of severe articular cartilage defects. We …

[HTML][HTML] Customized triphasic cartilage composite scaffold simulating hypoxic microenvironment for osteochondral regeneration

C Guo, Z Su, L Zhao, R Chen, Y Wang, Y Wu… - Composites Part B …, 2024 - Elsevier
The regeneration of the osteochondral complex in situ presents a significant challenge. The
inherent hypoxic microenvironment of cartilage plays a critical role in facilitating …

Dynamically cross-linked granular hydrogels for 3d printing and therapeutic delivery

HP Lee, R Davis Jr, TC Wang, KA Deo… - ACS Applied Bio …, 2023 - ACS Publications
Granular hydrogels have recently emerged as promising biomaterials for tissue engineering
and 3D-printing applications, addressing the limitations of bulk hydrogels while exhibiting …

Methods to achieve tissue-mimetic physicochemical properties in hydrogels for regenerative medicine and tissue engineering

R Fatima, B Almeida - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Hydrogels are water-swollen polymeric matrices with properties that are remarkably similar
in function to the extracellular matrix. For example, the polymer matrix provides structural …

Ionically annealed zwitterionic microgels for bioprinting of cartilaginous constructs

F Surman, M Asadikorayem, P Weber, D Weber… - …, 2024 - iopscience.iop.org
Foreign body response (FBR) is a pervasive problem for biomaterials used in tissue
engineering. Zwitterionic hydrogels have emerged as an effective solution to this problem …

Tissue engineering strategies hold promise for the repair of articular cartilage injury

C Yang, R Chen, C Chen, F Yang, H Xiao… - BioMedical Engineering …, 2024 - Springer
Articular cartilage damage and wear can result in cartilage degeneration, ultimately
culminating in osteoarthritis. Current surgical interventions offer limited capacity for cartilage …

Chondrocyte-derived apoptotic vesicles enhance stem cell biological function for the treatment of cartilage injury

H Yin, G Tian, J Zheng, Y Tang, R Yu, Z Yan… - Chemical Engineering …, 2024 - Elsevier
Transplanting chondrocytes has been extensively explored as a possible treatment option
for conditions linked to cartilage degradation. There are, however, a number of …