Polysaccharide-based hydrogels for medical devices, implants and tissue engineering: A review

D Sanjanwala, V Londhe, R Trivedi, S Bonde… - International Journal of …, 2024 - Elsevier
Hydrogels are highly biocompatible biomaterials composed of crosslinked three-
dimensional networks of hydrophilic polymers. Owing to their natural origin, polysaccharide …

Recent progress in using biomaterials as vitreous substitutes

X Su, MJ Tan, Z Li, M Wong, L Rajamani… - …, 2015 - ACS Publications
Vitreous substitutes are crucial adjuncts during vitreo-retinal surgery for retinal diseases
such as complicated retinal detachment, macular holes, complications of diabetic …

Hyaluronan and its derivatives for ophthalmology: Recent advances and future perspectives

GH Ángeles, K Nešporová - Carbohydrate Polymers, 2021 - Elsevier
Ophthalmic disorders are amid the most common pathologies worldwide. In this regard,
hyaluronan (HA) has gained widespread use in eye surgeries and treatment of eye …

A highly transparent tri-polymer complex in situ hydrogel of HA, collagen and four-arm-PEG as potential vitreous substitute

I Yadav, SD Purohit, H Singh, N Das, P Roy… - Biomedical …, 2021 - iopscience.iop.org
There is a requirement of removal and replacement of vitreous for various ophthalmic
diseases, eg retinopathy and retinal detachment. Clinical tamponades, eg silicone oil and …

Validation of hyaluronic acid-agar-based hydrogels as vitreous humor mimetics for in vitro drug and particle migration evaluations

SS Thakur, SK Shenoy, JS Suk, JS Hanes… - European Journal of …, 2020 - Elsevier
Artificial vitreous humor holds immense potential for use in in vitro intravitreal drug delivery
assays. In this study, we investigated rheological properties and drug or nanoparticle …

Vitreous substitutes: An overview of the properties, importance, and development

I Yadav, SD Purohit, H Singh… - … Research Part B …, 2021 - Wiley Online Library
Vitreous or vitreous humor is a complex transparent gel that fills the space between the lens
and retina of an eye and acts as a transparent medium that allows light to pass through it to …

A cross-linked hyaluronic acid hydrogel (Healaflow®) as a novel vitreous substitute

H Barth, S Crafoord, S Andréasson, F Ghosh - Graefe's Archive for Clinical …, 2016 - Springer
Purpose Vitrectomy requires the substitution of the natural vitreous, as well as tamponading
of retinal breaks. Clinically available alternatives such as gas and silicone oil have side …

[HTML][HTML] Desired properties of polymeric hydrogel vitreous substitute

S Qu, Y Tang, Z Ning, Y Zhou, H Wu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Vitreous replacement is a commonly employed method for treating a range of ocular
diseases, including posterior vitreous detachment, complex retinal detachment, diabetic …

Biocompatibility and efficacy of a linearly cross-linked sodium hyaluronic acid hydrogel as a retinal patch in rhegmatogenous retinal detachment repairment

C Zheng, H Xi, D Wen, Y Ke, X Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
To prevent the migration of retinal pigment epithelium (RPE) cells into the vitreous cavity
through retinal breaks after the pars plana vitrectomy for the repair of rhegmatogenous …

Inflammatory responses after vitrectomy with vitreous substitutes in a rabbit model

H Barth, S Crafoord, K Arnér, F Ghosh - Graefe's Archive for Clinical and …, 2019 - Springer
Purpose To investigate the inflammatory response of current and future potential vitreous
substitutes in an experimental in vivo vitrectomy model. Methods Twenty-five gauge pars …