The design of artificial enzymes has emerged as a promising tool for the generation of
potent biocatalysts able to promote new-to-nature reactions with improved catalytic …

Abstract Structure determination of proteins and enzymes by X-ray crystallography remains
the most widely used approach to complement functional and mechanistic studies …

Engineering proteins and enzymes with the desired functionality has broad applications in
molecular biology, biotechnology, biomedical sciences, health, and medicine. The vastness …

Considering the intrinsic toxicities of transition metals, their incorporation into drug therapies
must operate at minimal amounts while ensuring adequate catalytic activity within complex …

Effective electronic interactions between molecular catalysts and supports are critical for
heterogeneous enzyme mimics, yet they are frequently neglected in most catalyst designs …

Paper-based point-of-care (POC) devices exhibit the advantages of simplicity, rapidity, trim
sizes, and low cost, which are of particular importance for food safety, biological analysis …

Biocatalysis in ionic liquids (ILs) gained substantial interest due to solvent properties of the
ILs, such as near-zero vapor pressure, high thermal stability, and wide tunability. Enzymes …

Artificial metalloenzymes result from anchoring a metal cofactor within a host protein. Such
hybrid catalysts combine the selectivity and specificity of enzymes with the versatility of …

Artificial (transfer) hydrogenases have been developed for organic synthesis, but they rely
on precious metals. Native hydrogenases use Earth‐abundant metals, but these cannot be …

Technologies to improve the applicability of artificial metalloenzymes (ArMs) are gaining
considerable interest; one such approach is the immobilization of these biohybrid catalysts …