Tropism of the chikungunya virus

G Matusali, F Colavita, L Bordi, E Lalle, G Ippolito… - Viruses, 2019 - mdpi.com
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne virus that displays a large cell
and organ tropism, and causes a broad range of clinical symptoms in humans. It is …

Mosquito immunobiology: the intersection of vector health and vector competence

LC Bartholomay, K Michel - Annual review of entomology, 2018 - annualreviews.org
As holometabolous insects that occupy distinct aquatic and terrestrial environments in larval
and adult stages and utilize hematophagy for nutrient acquisition, mosquitoes are subjected …

Mosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti

GP Göertz, CBF Vogels, C Geertsema… - PLoS neglected …, 2017 - journals.plos.org
Background Zika virus (ZIKV) and chikungunya virus (CHIKV) are highly pathogenic
arthropod-borne viruses that are currently a serious health burden in the Americas, and …

Chikungunya virus dissemination from the midgut of Aedes aegypti is associated with temporal basal lamina degradation during bloodmeal digestion

S Dong, V Balaraman, AM Kantor, J Lin… - PLoS neglected …, 2017 - journals.plos.org
In the mosquito, the midgut epithelium is the initial tissue to become infected with an
arthropod-borne virus (arbovirus) that has been acquired from a vertebrate host along with a …

Chikungunya virus replication rate determines the capacity of crossing tissue barriers in mosquitoes

F Merwaiss, CV Filomatori, Y Susuki… - Journal of …, 2021 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a reemerging and rapidly spreading pathogen transmitted by
mosquitoes. The emergence of new epidemic variants of the virus is associated with genetic …

The midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape

S Dong, SK Behura, AWE Franz - BMC genomics, 2017 - Springer
Abstract Background The mosquito Aedes aegypti is the primary vector for medically
important arthropod-borne viruses, including chikungunya virus (CHIKV). Following oral …

Deciphering the dark proteome of Chikungunya virus

A Singh, A Kumar, R Yadav, VN Uversky, R Giri - Scientific reports, 2018 - nature.com
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus. The outbreak of CHIKV
infection has been seen in many tropical and subtropical regions of the biosphere. Current …

Zika Virus Dissemination from the Midgut of Aedes aegypti is Facilitated by Bloodmeal-Mediated Structural Modification of the Midgut Basal Lamina

Y Cui, DAG Grant, J Lin, X Yu, AWE Franz - Viruses, 2019 - mdpi.com
The arboviral disease cycle requires that key tissues in the arthropod vector become
persistently infected with the virus. The midgut is the first organ in the mosquito that needs to …

Laboratory strains of Aedes aegypti are competent to Brazilian Zika virus

AL Costa-da-Silva, RS Ioshino, HRC Araújo, BB Kojin… - PloS one, 2017 - journals.plos.org
The Zika virus outbreaks are unprecedented human threat in relation to congenital
malformations and neurological/autoimmune complications. Since this virus has high …

Determinants of Chikungunya and O'nyong-Nyong Virus Specificity for Infection of Aedes and Anopheles Mosquito Vectors

S Cottis, AA Blisnick, AB Failloux, KD Vernick - Viruses, 2023 - mdpi.com
Mosquito-borne diseases caused by viruses and parasites are responsible for more than
700 million infections each year. Anopheles and Aedes are the two major vectors for …