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The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …

Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Large intergenic noncoding RNAs (lincRNAs) are emerging as key regulators of diverse
cellular processes. Determining the function of individual lincRNAs remains a challenge …

Background The incidence of thyroid cancer has risen dramatically in the United States over
the past four decades, with similar patterns observed internationally. Thyroid cancer …

Although thousands of large intergenic non-coding RNAs (lincRNAs) have been identified in
mammals, few have been functionally characterized, leading to debate about their biological …

Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To
better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis …

In humans, the thyroid hormones T3 and T4 are synthesized in the thyroid gland in a
process that crucially involves the iodoglycoprotein thyroglobulin. The overall structure of …

Lineage-survival oncogenes are activated by somatic DNA alterations in cancers arising
from the cell lineages in which these genes play a role in normal development,. Here we …

Genetic variants responsible for susceptibility to obesity and its comorbidities among
Hispanic children have not been identified. The VIVA LA FAMILIA Study was designed to …