Beyond the X factor: relevance of sex hormones in NAFLD pathophysiology

S Della Torre - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being
frequently associated with obesity, unbalanced dietary regimens, and reduced physical …

Recent updates on animal models for understanding the etiopathogenesis of polycystic ovarian syndrome

L Corrie, M Gulati, SK Singh, B Kapoor, R Khursheed… - Life sciences, 2021 - Elsevier
Polycystic ovarian syndrome (PCOS) is the primary cause of female infertility affecting
several women worldwide. Changes in hormonal functions such as hyperandrogenism are …

The anti-inflammatory effects of Akkermansia muciniphila and its derivates in HFD/CCL4-induced murine model of liver injury

SKA Raftar, F Ashrafian, S Abdollahiyan, A Yadegar… - Scientific Reports, 2022 - nature.com
Inflammation plays a critical role in the promotion of hepatocyte damage and liver fibrosis. In
recent years the protective role of Akkermansia muciniphila, a next-generation beneficial …

[HTML][HTML] Microbial metabolites in non-alcoholic fatty liver disease

D Zhou, JG Fan - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising exponentially
worldwide. The spectrum of NAFLD includes non-alcoholic fatty liver, non-alcoholic …

无抽搐电休克疗法对精神分裂症患者的治疗效果和脑内及不同脑区神经递质水平的影响研究

范桂红, 何俊, 庞高峰, 李辰, 江庐山, 方惠民, 王舟 - 中国全科医学, 2022 - chinagp.net
背景目前, 采用脑涨落图仪分析精神分裂症患者多个脑区神经递质功能特点的研究较多,
也有关于无抽搐电休克疗法(MECT) 对精神分裂症患者脑内神经递质影响的研究, 但关于MECT …

A network pharmacology approach to explore the mechanisms of Erxian decoction in polycystic ovary syndrome

L Liu, B Du, H Zhang, X Guo, Z Zhou, A Xiu, C Liu… - Chinese Medicine, 2018 - Springer
Background Polycystic ovary syndrome (PCOS) significantly affects women's health and well-
being. To explore the pharmacological basis of the Erxian decoction (EXD) action in PCOS …

Controlled attenuation parameters to assess liver steatosis in obese patients with polycystic ovary syndrome

D Wang, N Nan, H Bing, B He - Frontiers in Endocrinology, 2023 - frontiersin.org
Objectives This study was performed to investigate the changes and influencing factors of
liver controlled attenuation parameter (CAP) in obese patients with polycystic ovary …

Insight into metabolic dysregulation of polycystic ovary syndrome utilizing metabolomic signatures: a narrative review

A Naigaonkar, R Dadachanji, M Kumari… - Critical Reviews in …, 2024 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a complex multifactorial endocrinopathy affecting
reproductive aged women globally, whose presentation is strongly influenced by genetic …

Machine‐Learning Prediction of Oral Drug‐Induced Liver Injury (DILI) via Multiple Features and Endpoints

X Liu, D Zheng, Y Zhong, Z Xia, H Luo… - BioMed Research …, 2020 - Wiley Online Library
Drug discovery is a costly process which usually takes more than 10 years and billions of
dollars for one successful drug to enter the market. Despite all the safety tests, drugs may …

D-glucaro-1, 4-lactone improves Diethylnitrosamine induced hepatocellular carcinoma in rats via the uric acid-ROS pathway

H Cai, Y Zhang, J Wang, Y Deng, J Liu, Z Wu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Liuwei dihuang pills is a famous Traditional Chinese
Medicine with various anti-cancer properties. Over 50 pharmaceutical manufacturers …