Results Twenty-two studies (17 observational and 5 RCTs) were included. There was a
significant improvement in 25-hydroxyvitamin D (MD 24.1 ng/ml, 95% CI 19.6 to 28.6) and …

Vitamin D is one of the most frequently used medicinal prod-ucts around the world. The
dietary intake is irregular because few food items contain vitamin D and is usually well …

Disturbances in mineral and bone metabolism are common in patients with CKD. A large
body of evidence indicates that these derangements are associated with increased mortality …

Context: Vitamin D has been shown to influence cardiac contractility and myocardial calcium
homeostasis. Objectives: We aimed to elucidate whether insufficient vitamin D status is …

Background—Cardiovascular disease is the leading cause of death among those with
diabetes mellitus. Vitamin D deficiency is associated with an increased risk of cardiovascular …

Background: Kidney disease has been identified as a risk factor for vitamin D deficiency in
hospitalized patients, and low levels of 25-hydroxyvitamin D have been suggested to be a …

Although the kidney was initially thought to be the sole organ responsible for the production
of 1, 25 (OH) 2 D via the enzyme CYP27b1, it is now appreciated that the expression of …

Serum levels of 1, 25-dihydroxyvitamin D, 24, 25-dihydroxyvitamin D, and 25-hydroxyvitamin
D in nondialyzed patients with chronic renal failure. Background In patients with chronic …

In vitro, monocyte 1α-hydroxylase converts 25-hydroxyvitamin D [25 (OH) D] to 1, 25-
dihydroxyvitamin D to regulate local innate immune responses, but whether 25 (OH) D …

Recent advances in the understanding of vitamin D have revolutionized our view of this old
nutritional factor and suggested that it has much wider effects on the body than ever …