Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …

Spinal cord injury (SCI) is a debilitating condition, often leading to severe motor, sensory, or
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …

Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

Major depressive disorder (MDD) is a life‐threatening disease that presents several
characteristics. The pathogenesis of depression still remains poorly understood. Moreover …

Central nervous system (CNS) diseases are the leading cause of death worldwide. By
performing compensatory functions and improving the inflammatory microenvironment, the …

Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Over the past decades, peptides and proteins have been increasingly important in the
treatment of various human diseases and conditions owing to their specificity, potency, and …

Increasing evidence foresees the secretome of neural stem cells (NSCs) to confer
superimposable beneficial properties as exogenous NSC transplants in experimental …

Hundreds of thousands of people suffer spinal cord injuries each year. The experimental
application of stem cells following spinal cord injury has opened a new era to promote …

Periprosthetic osteolysis (PPO) along with aseptic loosening (AL) caused by wear particles
after artificial joint replacement is the key factor in surgical failure and subsequent revision …